Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability

X-ray free-electron lasers produce bright femtosecond X-ray pulses. Here, the authors use a two-colour X-ray free-electron laser beam for simultaneous two-wavelength data collection and show that protein structures can be determined with multiple wavelength anomalous dispersion phasing, which is imp...

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Autores principales: Alexander Gorel, Koji Motomura, Hironobu Fukuzawa, R. Bruce Doak, Marie Luise Grünbein, Mario Hilpert, Ichiro Inoue, Marco Kloos, Gabriela Kovácsová, Eriko Nango, Karol Nass, Christopher M. Roome, Robert L. Shoeman, Rie Tanaka, Kensuke Tono, Yasumasa Joti, Makina Yabashi, So Iwata, Lutz Foucar, Kiyoshi Ueda, Thomas R. M. Barends, Ilme Schlichting
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/44d615b724fa4a20b4208d2dc0106a3d
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spelling oai:doaj.org-article:44d615b724fa4a20b4208d2dc0106a3d2021-12-02T14:41:20ZMulti-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability10.1038/s41467-017-00754-72041-1723https://doaj.org/article/44d615b724fa4a20b4208d2dc0106a3d2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00754-7https://doaj.org/toc/2041-1723X-ray free-electron lasers produce bright femtosecond X-ray pulses. Here, the authors use a two-colour X-ray free-electron laser beam for simultaneous two-wavelength data collection and show that protein structures can be determined with multiple wavelength anomalous dispersion phasing, which is important for difficult-to-phase projects.Alexander GorelKoji MotomuraHironobu FukuzawaR. Bruce DoakMarie Luise GrünbeinMario HilpertIchiro InoueMarco KloosGabriela KovácsováEriko NangoKarol NassChristopher M. RoomeRobert L. ShoemanRie TanakaKensuke TonoYasumasa JotiMakina YabashiSo IwataLutz FoucarKiyoshi UedaThomas R. M. BarendsIlme SchlichtingNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alexander Gorel
Koji Motomura
Hironobu Fukuzawa
R. Bruce Doak
Marie Luise Grünbein
Mario Hilpert
Ichiro Inoue
Marco Kloos
Gabriela Kovácsová
Eriko Nango
Karol Nass
Christopher M. Roome
Robert L. Shoeman
Rie Tanaka
Kensuke Tono
Yasumasa Joti
Makina Yabashi
So Iwata
Lutz Foucar
Kiyoshi Ueda
Thomas R. M. Barends
Ilme Schlichting
Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability
description X-ray free-electron lasers produce bright femtosecond X-ray pulses. Here, the authors use a two-colour X-ray free-electron laser beam for simultaneous two-wavelength data collection and show that protein structures can be determined with multiple wavelength anomalous dispersion phasing, which is important for difficult-to-phase projects.
format article
author Alexander Gorel
Koji Motomura
Hironobu Fukuzawa
R. Bruce Doak
Marie Luise Grünbein
Mario Hilpert
Ichiro Inoue
Marco Kloos
Gabriela Kovácsová
Eriko Nango
Karol Nass
Christopher M. Roome
Robert L. Shoeman
Rie Tanaka
Kensuke Tono
Yasumasa Joti
Makina Yabashi
So Iwata
Lutz Foucar
Kiyoshi Ueda
Thomas R. M. Barends
Ilme Schlichting
author_facet Alexander Gorel
Koji Motomura
Hironobu Fukuzawa
R. Bruce Doak
Marie Luise Grünbein
Mario Hilpert
Ichiro Inoue
Marco Kloos
Gabriela Kovácsová
Eriko Nango
Karol Nass
Christopher M. Roome
Robert L. Shoeman
Rie Tanaka
Kensuke Tono
Yasumasa Joti
Makina Yabashi
So Iwata
Lutz Foucar
Kiyoshi Ueda
Thomas R. M. Barends
Ilme Schlichting
author_sort Alexander Gorel
title Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability
title_short Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability
title_full Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability
title_fullStr Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability
title_full_unstemmed Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability
title_sort multi-wavelength anomalous diffraction de novo phasing using a two-colour x-ray free-electron laser with wide tunability
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/44d615b724fa4a20b4208d2dc0106a3d
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