Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability
X-ray free-electron lasers produce bright femtosecond X-ray pulses. Here, the authors use a two-colour X-ray free-electron laser beam for simultaneous two-wavelength data collection and show that protein structures can be determined with multiple wavelength anomalous dispersion phasing, which is imp...
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2017
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oai:doaj.org-article:44d615b724fa4a20b4208d2dc0106a3d2021-12-02T14:41:20ZMulti-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability10.1038/s41467-017-00754-72041-1723https://doaj.org/article/44d615b724fa4a20b4208d2dc0106a3d2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00754-7https://doaj.org/toc/2041-1723X-ray free-electron lasers produce bright femtosecond X-ray pulses. Here, the authors use a two-colour X-ray free-electron laser beam for simultaneous two-wavelength data collection and show that protein structures can be determined with multiple wavelength anomalous dispersion phasing, which is important for difficult-to-phase projects.Alexander GorelKoji MotomuraHironobu FukuzawaR. Bruce DoakMarie Luise GrünbeinMario HilpertIchiro InoueMarco KloosGabriela KovácsováEriko NangoKarol NassChristopher M. RoomeRobert L. ShoemanRie TanakaKensuke TonoYasumasa JotiMakina YabashiSo IwataLutz FoucarKiyoshi UedaThomas R. M. BarendsIlme SchlichtingNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017) |
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Science Q Alexander Gorel Koji Motomura Hironobu Fukuzawa R. Bruce Doak Marie Luise Grünbein Mario Hilpert Ichiro Inoue Marco Kloos Gabriela Kovácsová Eriko Nango Karol Nass Christopher M. Roome Robert L. Shoeman Rie Tanaka Kensuke Tono Yasumasa Joti Makina Yabashi So Iwata Lutz Foucar Kiyoshi Ueda Thomas R. M. Barends Ilme Schlichting Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability |
description |
X-ray free-electron lasers produce bright femtosecond X-ray pulses. Here, the authors use a two-colour X-ray free-electron laser beam for simultaneous two-wavelength data collection and show that protein structures can be determined with multiple wavelength anomalous dispersion phasing, which is important for difficult-to-phase projects. |
format |
article |
author |
Alexander Gorel Koji Motomura Hironobu Fukuzawa R. Bruce Doak Marie Luise Grünbein Mario Hilpert Ichiro Inoue Marco Kloos Gabriela Kovácsová Eriko Nango Karol Nass Christopher M. Roome Robert L. Shoeman Rie Tanaka Kensuke Tono Yasumasa Joti Makina Yabashi So Iwata Lutz Foucar Kiyoshi Ueda Thomas R. M. Barends Ilme Schlichting |
author_facet |
Alexander Gorel Koji Motomura Hironobu Fukuzawa R. Bruce Doak Marie Luise Grünbein Mario Hilpert Ichiro Inoue Marco Kloos Gabriela Kovácsová Eriko Nango Karol Nass Christopher M. Roome Robert L. Shoeman Rie Tanaka Kensuke Tono Yasumasa Joti Makina Yabashi So Iwata Lutz Foucar Kiyoshi Ueda Thomas R. M. Barends Ilme Schlichting |
author_sort |
Alexander Gorel |
title |
Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability |
title_short |
Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability |
title_full |
Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability |
title_fullStr |
Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability |
title_full_unstemmed |
Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability |
title_sort |
multi-wavelength anomalous diffraction de novo phasing using a two-colour x-ray free-electron laser with wide tunability |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/44d615b724fa4a20b4208d2dc0106a3d |
work_keys_str_mv |
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