Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I

Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I

ABSTRACT Stimulation of the antiviral response depends on the sensing of viral pathogen-associated molecular patterns (PAMPs) by specialized cellular proteins. During infection with RNA viruses, 5′-di- or -triphosphates accompanying specific single or double-stranded RNA motifs trigger signaling of...

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Autores principales: Jie Xu, Xiomara Mercado-López, Jennifer T. Grier, Won-keun Kim, Lauren F. Chun, Edward B. Irvine, Yoandris Del Toro Duany, Alison Kell, Sun Hur, Michael Gale, Arjun Raj, Carolina B. López
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/44e61581f5e346218856bd25e4a58991
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