Acquisition of a side population fraction augments malignant phenotype in ovarian cancer

Acquisition of a side population fraction augments malignant phenotype in ovarian cancer

Abstract Side population (SP) cells harbor malignant phenotypes in cancer. The aim of this study was to identify genes that modulate the proportion of ovarian cancer SP cells. Using a shRNA library targeting 15,000 genes, a functional genomics screen was performed to identify genes whose suppression...

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Autores principales: Koji Yamanoi, Tsukasa Baba, Kaoru Abiko, Junzo Hamanishi, Ken Yamaguchi, Ryusuke Murakami, Mana Taki, Yuko Hosoe, Susan K. Murphy, Ikuo Konishi, Masaki Mandai, Noriomi Matsumura
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/44e8b3ffbba9498a88db3b0789ca4998
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