Single-cell analysis reveals new evolutionary complexity in uveal melanoma
Uveal melanoma is highly metastatic and unresponsive to checkpoint immunotherapy. Here, the authors present single-cell transcriptomics of 59,915 cells in 8 primary and 3 metastatic samples, highlighting the diversity of the tumour microenvironment.
Guardado en:
Autores principales: | Michael A. Durante, Daniel A. Rodriguez, Stefan Kurtenbach, Jeffim N. Kuznetsov, Margaret I. Sanchez, Christina L. Decatur, Helen Snyder, Lynn G. Feun, Alan S. Livingstone, J. William Harbour |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/44e8def81b794cf189b9ab19348ac21d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Punctuated evolution of canonical genomic aberrations in uveal melanoma
por: Matthew G. Field, et al.
Publicado: (2018) -
Multiregional genetic evolution of metastatic uveal melanoma
por: Daniel A. Rodriguez, et al.
Publicado: (2021) -
Uveal Melanoma Metastasis
por: Ernesto Rossi, et al.
Publicado: (2021) -
Microincisional vitrectomy for retinal detachment in I-125 brachytherapy-treated patients with posterior uveal malignant melanoma
por: Lonngi M, et al.
Publicado: (2013) -
Uveal melanoma: Long-term survival.
por: Tomas Radivoyevitch, et al.
Publicado: (2021)