Contact Challenge of Cattle with Foot-and-Mouth Disease Virus Validates the Role of the Nasopharyngeal Epithelium as the Site of Primary and Persistent Infection

Contact Challenge of Cattle with Foot-and-Mouth Disease Virus Validates the Role of the Nasopharyngeal Epithelium as the Site of Primary and Persistent Infection

ABSTRACT The pathogenesis of foot-and-mouth disease virus (FMDV) in cattle was investigated through early and late stages of infection by use of an optimized experimental model for controlled contact exposure. Time-limited exposure of cattle to FMDV-infected pigs led to primary FMDV infection of the...

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Bibliographic Details
Main Authors: Carolina Stenfeldt, Ethan J. Hartwig, George R. Smoliga, Rachel Palinski, Ediane B. Silva, Miranda R. Bertram, Ian H. Fish, Steven J. Pauszek, Jonathan Arzt
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
foot-and-mouth disease
foot-and-mouth disease virus
FMD
FMDV
cattle
pigs
Microbiology
QR1-502
Online Access:https://doaj.org/article/4509bb07b16d41eaaa39950d3f33abf4
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