Do Common Beans (<i>Phaseolus vulgaris</i> L.) Promote Good Health in Humans? A Systematic Review and Meta-Analysis of Clinical and Randomized Controlled Trials

The common bean is a nutrient-dense food empirically known to have beneficial effects on human health. Many studies have looked at the effects of “pulses” on different health issues, providing general overviews of the importance of each pulse in health studies. This study systematically reviews and...

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Autores principales:	Eileen Bogweh Nchanji, Odhiambo Collins Ageyo
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	common beans cardiovascular diseases diabetes mellitus obesity cancers human trials Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/4512b2ae791743e0a44adc3003077e99
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spelling	oai:doaj.org-article:4512b2ae791743e0a44adc3003077e992021-11-25T18:33:18ZDo Common Beans (<i>Phaseolus vulgaris</i> L.) Promote Good Health in Humans? A Systematic Review and Meta-Analysis of Clinical and Randomized Controlled Trials10.3390/nu131137012072-6643https://doaj.org/article/4512b2ae791743e0a44adc3003077e992021-10-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/3701https://doaj.org/toc/2072-6643The common bean is a nutrient-dense food empirically known to have beneficial effects on human health. Many studies have looked at the effects of “pulses” on different health issues, providing general overviews of the importance of each pulse in health studies. This study systematically reviews and provides meta-analyses of the effect of bean extract as a supplement or whole bean on four health issues (cardiovascular diseases, diabetes mellitus, obesity, and cancers) from a dissection of clinical and randomized controlled trials using human subjects. A digital search in PubMed and Google Scholar<sup>TM</sup> resulted in 340 articles, with only 23 peer-reviewed articles matching our inclusion criteria. Findings indicated that common beans reduced LDL cholesterol by 19 percent, risk of cardiovascular disease (CVD) by 11 percent, and coronary heart disease (CHD) by 22 percent. Besides this, we noted variances in the literature on cancer findings, with some authors stating it reduced the proliferation of some kinds of tumor cells and reduced the growth of polyps, while others did not specifically examine cancers but the predisposing factors alone. However, diabetes studies indicated that the postprandial glucose level at the peak of 60 min for common bean consumers was low (mean difference = −2.01; 95% CI [−4.6, −0.63]), but the difference between the treated and control was not significant, and there was a high level of heterogeneity among studies (I<sup>2</sup> = 98%). Only obesity studies indicated a significantly high level of weight gain among control groups (mean difference = 1.62; 95% CI [0.37, 2.86]). There is a need for additional clinical trials using a standardized measure to indicate the real effect of the common bean on health.Eileen Bogweh NchanjiOdhiambo Collins AgeyoMDPI AGarticlecommon beanscardiovascular diseasesdiabetes mellitusobesitycancershuman trialsNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 3701, p 3701 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	common beans cardiovascular diseases diabetes mellitus obesity cancers human trials Nutrition. Foods and food supply TX341-641
spellingShingle	common beans cardiovascular diseases diabetes mellitus obesity cancers human trials Nutrition. Foods and food supply TX341-641 Eileen Bogweh Nchanji Odhiambo Collins Ageyo Do Common Beans (<i>Phaseolus vulgaris</i> L.) Promote Good Health in Humans? A Systematic Review and Meta-Analysis of Clinical and Randomized Controlled Trials
description	The common bean is a nutrient-dense food empirically known to have beneficial effects on human health. Many studies have looked at the effects of “pulses” on different health issues, providing general overviews of the importance of each pulse in health studies. This study systematically reviews and provides meta-analyses of the effect of bean extract as a supplement or whole bean on four health issues (cardiovascular diseases, diabetes mellitus, obesity, and cancers) from a dissection of clinical and randomized controlled trials using human subjects. A digital search in PubMed and Google Scholar<sup>TM</sup> resulted in 340 articles, with only 23 peer-reviewed articles matching our inclusion criteria. Findings indicated that common beans reduced LDL cholesterol by 19 percent, risk of cardiovascular disease (CVD) by 11 percent, and coronary heart disease (CHD) by 22 percent. Besides this, we noted variances in the literature on cancer findings, with some authors stating it reduced the proliferation of some kinds of tumor cells and reduced the growth of polyps, while others did not specifically examine cancers but the predisposing factors alone. However, diabetes studies indicated that the postprandial glucose level at the peak of 60 min for common bean consumers was low (mean difference = −2.01; 95% CI [−4.6, −0.63]), but the difference between the treated and control was not significant, and there was a high level of heterogeneity among studies (I<sup>2</sup> = 98%). Only obesity studies indicated a significantly high level of weight gain among control groups (mean difference = 1.62; 95% CI [0.37, 2.86]). There is a need for additional clinical trials using a standardized measure to indicate the real effect of the common bean on health.
format	article
author	Eileen Bogweh Nchanji Odhiambo Collins Ageyo
author_facet	Eileen Bogweh Nchanji Odhiambo Collins Ageyo
author_sort	Eileen Bogweh Nchanji
title	Do Common Beans (<i>Phaseolus vulgaris</i> L.) Promote Good Health in Humans? A Systematic Review and Meta-Analysis of Clinical and Randomized Controlled Trials
title_short	Do Common Beans (<i>Phaseolus vulgaris</i> L.) Promote Good Health in Humans? A Systematic Review and Meta-Analysis of Clinical and Randomized Controlled Trials
title_full	Do Common Beans (<i>Phaseolus vulgaris</i> L.) Promote Good Health in Humans? A Systematic Review and Meta-Analysis of Clinical and Randomized Controlled Trials
title_fullStr	Do Common Beans (<i>Phaseolus vulgaris</i> L.) Promote Good Health in Humans? A Systematic Review and Meta-Analysis of Clinical and Randomized Controlled Trials
title_full_unstemmed	Do Common Beans (<i>Phaseolus vulgaris</i> L.) Promote Good Health in Humans? A Systematic Review and Meta-Analysis of Clinical and Randomized Controlled Trials
title_sort	do common beans (<i>phaseolus vulgaris</i> l.) promote good health in humans? a systematic review and meta-analysis of clinical and randomized controlled trials
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/4512b2ae791743e0a44adc3003077e99
work_keys_str_mv	AT eileenbogwehnchanji docommonbeansiphaseolusvulgarisilpromotegoodhealthinhumansasystematicreviewandmetaanalysisofclinicalandrandomizedcontrolledtrials AT odhiambocollinsageyo docommonbeansiphaseolusvulgarisilpromotegoodhealthinhumansasystematicreviewandmetaanalysisofclinicalandrandomizedcontrolledtrials
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Do Common Beans (<i>Phaseolus vulgaris</i> L.) Promote Good Health in Humans? A Systematic Review and Meta-Analysis of Clinical and Randomized Controlled Trials

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