Droplet barcoding for massively parallel single-molecule deep sequencing
The ability to accurately sequence long DNA molecules is important across biology. Here, Lan et al. report a droplet-based method that barcodes single DNA molecules, allowing the full-length molecules to be sequenced with multi-fold coverage using short-read next-generation sequencing.
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Auteurs principaux: | Freeman Lan, John R. Haliburton, Aaron Yuan, Adam R. Abate |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2016
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Sujets: | |
Accès en ligne: | https://doaj.org/article/4515e37d471a4e2ab6daee8b7d910e97 |
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