Droplet barcoding for massively parallel single-molecule deep sequencing

The ability to accurately sequence long DNA molecules is important across biology. Here, Lan et al. report a droplet-based method that barcodes single DNA molecules, allowing the full-length molecules to be sequenced with multi-fold coverage using short-read next-generation sequencing.

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Detalles Bibliográficos
Autores principales: Freeman Lan, John R. Haliburton, Aaron Yuan, Adam R. Abate
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/4515e37d471a4e2ab6daee8b7d910e97
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