Age-specific differences in the dynamics of protective immunity to influenza
Protective immunity after influenza virus infection is poorly understood. Here, the authors quantify the dynamics of immunity against influenza A virus infections by fitting individual-level mechanistic models to longitudinal serology, and find that the form and dynamics of protection differ between...
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Nature Portfolio
2019
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oai:doaj.org-article:4516db8cd934415db46e3d01cea399902021-12-02T16:51:01ZAge-specific differences in the dynamics of protective immunity to influenza10.1038/s41467-019-09652-62041-1723https://doaj.org/article/4516db8cd934415db46e3d01cea399902019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09652-6https://doaj.org/toc/2041-1723Protective immunity after influenza virus infection is poorly understood. Here, the authors quantify the dynamics of immunity against influenza A virus infections by fitting individual-level mechanistic models to longitudinal serology, and find that the form and dynamics of protection differ between children and adults.Sylvia RanjevaRahul SubramanianVicky J. FangGabriel M. LeungDennis K. M. IpRanawaka A. P. M. PereraJ. S. Malik PeirisBenjamin J. CowlingSarah CobeyNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019) |
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Science Q Sylvia Ranjeva Rahul Subramanian Vicky J. Fang Gabriel M. Leung Dennis K. M. Ip Ranawaka A. P. M. Perera J. S. Malik Peiris Benjamin J. Cowling Sarah Cobey Age-specific differences in the dynamics of protective immunity to influenza |
description |
Protective immunity after influenza virus infection is poorly understood. Here, the authors quantify the dynamics of immunity against influenza A virus infections by fitting individual-level mechanistic models to longitudinal serology, and find that the form and dynamics of protection differ between children and adults. |
format |
article |
author |
Sylvia Ranjeva Rahul Subramanian Vicky J. Fang Gabriel M. Leung Dennis K. M. Ip Ranawaka A. P. M. Perera J. S. Malik Peiris Benjamin J. Cowling Sarah Cobey |
author_facet |
Sylvia Ranjeva Rahul Subramanian Vicky J. Fang Gabriel M. Leung Dennis K. M. Ip Ranawaka A. P. M. Perera J. S. Malik Peiris Benjamin J. Cowling Sarah Cobey |
author_sort |
Sylvia Ranjeva |
title |
Age-specific differences in the dynamics of protective immunity to influenza |
title_short |
Age-specific differences in the dynamics of protective immunity to influenza |
title_full |
Age-specific differences in the dynamics of protective immunity to influenza |
title_fullStr |
Age-specific differences in the dynamics of protective immunity to influenza |
title_full_unstemmed |
Age-specific differences in the dynamics of protective immunity to influenza |
title_sort |
age-specific differences in the dynamics of protective immunity to influenza |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/4516db8cd934415db46e3d01cea39990 |
work_keys_str_mv |
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1718382973586243584 |