The measurement of Digoxin serum level (DSL) in patients with heart disease and its relation with age

Background and objective: With regard to the extensive use of digoxin in patients with heart disease and its high prevalence of toxicity, this study was done to measure the digoxin serum level (DSL) in patients with or without symptoms of poisoning and determine its relation with age. Methods: This...

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Autores principales: MT Salehi Omran, MR Khosoosi Niaki, SA Hashemi, F Saberian
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Publicado: Babol University of Medical Sciences 2005
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Acceso en línea:https://doaj.org/article/45177ac49ec54338b052203eec1e3edd
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spelling oai:doaj.org-article:45177ac49ec54338b052203eec1e3edd2021-11-10T09:14:41ZThe measurement of Digoxin serum level (DSL) in patients with heart disease and its relation with age1561-41072251-7170https://doaj.org/article/45177ac49ec54338b052203eec1e3edd2005-07-01T00:00:00Zhttp://jbums.org/article-1-2624-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and objective: With regard to the extensive use of digoxin in patients with heart disease and its high prevalence of toxicity, this study was done to measure the digoxin serum level (DSL) in patients with or without symptoms of poisoning and determine its relation with age. Methods: This study was performed on 441 patients who used digoxin in Babol Shahid Beheshti hospital in 1999-2003. Digoxin has been used for a long time by these patients and the cause of hospitalization was symptoms related to digoxin and primary disease. DSL was measured after history taking and information about the presence of poisoning symptoms. Finding: From 441 patients, 63 cases were toxic and 378 cases were non-toxic. Among 63 toxic cases, DSL in 27 cases was more than 2 ng/dl in serum that 82% of them were under 70 years old and DSL in 36 cases was less than 2 ng/dl in serum that 95% of them were over 70 years. From 378 non-toxic cases, 42 cases (11%) were over 70 years that DSL in all of them was less than 2 ng/dl and 336 (89%) were under 70 years that DSL in 3 (4%) and 323 (96%) was more and less than 2 ng/dl, respectively. Conclusion: Although, the most DSL in non-toxic patients was more than 2 ng/dl but DSL less than 2 ng/dl can also cause digoxin toxicity (Especially in patients more than 70 years).MT Salehi OmranMR Khosoosi NiakiSA HashemiF SaberianBabol University of Medical Sciencesarticledigoxin leveltoxicityheart disease patientsMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 7, Iss 3, Pp 69-72 (2005)
institution DOAJ
collection DOAJ
language EN
FA
topic digoxin level
toxicity
heart disease patients
Medicine
R
Medicine (General)
R5-920
spellingShingle digoxin level
toxicity
heart disease patients
Medicine
R
Medicine (General)
R5-920
MT Salehi Omran
MR Khosoosi Niaki
SA Hashemi
F Saberian
The measurement of Digoxin serum level (DSL) in patients with heart disease and its relation with age
description Background and objective: With regard to the extensive use of digoxin in patients with heart disease and its high prevalence of toxicity, this study was done to measure the digoxin serum level (DSL) in patients with or without symptoms of poisoning and determine its relation with age. Methods: This study was performed on 441 patients who used digoxin in Babol Shahid Beheshti hospital in 1999-2003. Digoxin has been used for a long time by these patients and the cause of hospitalization was symptoms related to digoxin and primary disease. DSL was measured after history taking and information about the presence of poisoning symptoms. Finding: From 441 patients, 63 cases were toxic and 378 cases were non-toxic. Among 63 toxic cases, DSL in 27 cases was more than 2 ng/dl in serum that 82% of them were under 70 years old and DSL in 36 cases was less than 2 ng/dl in serum that 95% of them were over 70 years. From 378 non-toxic cases, 42 cases (11%) were over 70 years that DSL in all of them was less than 2 ng/dl and 336 (89%) were under 70 years that DSL in 3 (4%) and 323 (96%) was more and less than 2 ng/dl, respectively. Conclusion: Although, the most DSL in non-toxic patients was more than 2 ng/dl but DSL less than 2 ng/dl can also cause digoxin toxicity (Especially in patients more than 70 years).
format article
author MT Salehi Omran
MR Khosoosi Niaki
SA Hashemi
F Saberian
author_facet MT Salehi Omran
MR Khosoosi Niaki
SA Hashemi
F Saberian
author_sort MT Salehi Omran
title The measurement of Digoxin serum level (DSL) in patients with heart disease and its relation with age
title_short The measurement of Digoxin serum level (DSL) in patients with heart disease and its relation with age
title_full The measurement of Digoxin serum level (DSL) in patients with heart disease and its relation with age
title_fullStr The measurement of Digoxin serum level (DSL) in patients with heart disease and its relation with age
title_full_unstemmed The measurement of Digoxin serum level (DSL) in patients with heart disease and its relation with age
title_sort measurement of digoxin serum level (dsl) in patients with heart disease and its relation with age
publisher Babol University of Medical Sciences
publishDate 2005
url https://doaj.org/article/45177ac49ec54338b052203eec1e3edd
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AT mrkhosoosiniaki themeasurementofdigoxinserumleveldslinpatientswithheartdiseaseanditsrelationwithage
AT sahashemi themeasurementofdigoxinserumleveldslinpatientswithheartdiseaseanditsrelationwithage
AT fsaberian themeasurementofdigoxinserumleveldslinpatientswithheartdiseaseanditsrelationwithage
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AT mrkhosoosiniaki measurementofdigoxinserumleveldslinpatientswithheartdiseaseanditsrelationwithage
AT sahashemi measurementofdigoxinserumleveldslinpatientswithheartdiseaseanditsrelationwithage
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