Submicron-Sized Vermiculite Assisted Oregano Oil for Controlled Release and Long-Term Bacterial Inhibition

Oregano essential oil (OEO) is a natural compound consisting of potent antibiotic molecules. Its volatility is the major obstacle against the transportation and anti-bacterial performance. In this work, submicron-sized vermiculite (SMV) particles were prepared from Australian vermiculite clay by bal...

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Autores principales: Sukitha Geethma Kothalawala, Jun Zhang, Yue Wang, Chengzhong Yu
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/451a0b00bfc04f579df23998e1102ca1
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Sumario:Oregano essential oil (OEO) is a natural compound consisting of potent antibiotic molecules. Its volatility is the major obstacle against the transportation and anti-bacterial performance. In this work, submicron-sized vermiculite (SMV) particles were prepared from Australian vermiculite clay by ball milling, and tested as a potential particulate-carrier for OEO. The loading of OEO by SMV can be easily achieved by mechanical mixing. Compared to raw vermiculite and free OEO, the OEO-loaded SMV displayed sustained isothermal release behaviour of OEO and demonstrated enhanced antibacterial performance in in vitro antibacterial tests against <i>Escherichia coli</i> (<i>E. coli</i>) and <i>Staphylococcus</i> <i>epidermidis</i> (<i>S. epidermidis</i>). This study provides a facile and commercially viable approach in designing advantageous carriers for volatile actives in antimicrobial applications.