COMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEA

Objective: To compare World Health Organization treatment for acute watery diarrhea in children with and without probiotic Saccharomyces boulardii in terms of mean duration of diarrhea. Study Design: Comparative cross sectional study. Place and Duration of Study: Combined Military Hospital Tar...

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Autores principales: Ali Raza, Muhammad Zahid, Ehsan Qadir, Nazir Ahmed Malik, Sohail Aslam, Kashif Siddique
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Publicado: Army Medical College Rawalpindi 2020
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spelling oai:doaj.org-article:451b3790030b4625b6a46a36cdcec12e2021-12-02T17:20:37ZCOMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEA0030-96482411-8842https://doaj.org/article/451b3790030b4625b6a46a36cdcec12e2020-10-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/5566https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare World Health Organization treatment for acute watery diarrhea in children with and without probiotic Saccharomyces boulardii in terms of mean duration of diarrhea. Study Design: Comparative cross sectional study. Place and Duration of Study: Combined Military Hospital Tarbela, Pakistan, from Jan 2019 to Jul 2019. Methodology: Eighty four children were enrolled in this study using inclusion and exclusion criteria. Two groups were made. Group A was treated with oral Zinc (10mg for <6 months old, 20mg for >6 months old for 14 days); low osmolarity Oral rehydration salt by 5 ml/kg per hour and continuation of nutritious feeding. Group B was treated with 250mg twice daily Sacchromyces boulardii along with oral Zinc (10mg for <6months old, 20mg for >6 months old for 14 days); low osmolarity Oral rehydration salt by 5 ml/kg per hour and continuation of nutritious feeding. Assessment included anthropometric measurements, hydration status, daily frequency and consistency of stools. Baseline investigations were sent to Combined Military Hospital, Tarbela Laboratory. Data was recorded on a specially designed proforma. Results: Duration of diarrhea was significantly lower in children who were given Saccharomyces boulardii with Zinc as compared to children who were given Zinc alone. i.e., group-A (Zinc): 53.31 hrs vs. group-B (Zinc+ Saccharomyces boulardii): 36.37 hrs, p<0.001 Conclusion: Saccharomyces boulardii can be effectively used with Zinc to treat acute watery diarrhea in children less than five years of age as it significantly reduces mean duration of diarrhea.Ali RazaMuhammad ZahidEhsan QadirNazir Ahmed MalikSohail AslamKashif SiddiqueArmy Medical College Rawalpindiarticlechildrendiarrheaprobioticsaccharomyces boulardiiworld health organizationMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 5, Pp 1371-1375 (2020)
institution DOAJ
collection DOAJ
language EN
topic children
diarrhea
probiotic
saccharomyces boulardii
world health organization
Medicine
R
Medicine (General)
R5-920
spellingShingle children
diarrhea
probiotic
saccharomyces boulardii
world health organization
Medicine
R
Medicine (General)
R5-920
Ali Raza
Muhammad Zahid
Ehsan Qadir
Nazir Ahmed Malik
Sohail Aslam
Kashif Siddique
COMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEA
description Objective: To compare World Health Organization treatment for acute watery diarrhea in children with and without probiotic Saccharomyces boulardii in terms of mean duration of diarrhea. Study Design: Comparative cross sectional study. Place and Duration of Study: Combined Military Hospital Tarbela, Pakistan, from Jan 2019 to Jul 2019. Methodology: Eighty four children were enrolled in this study using inclusion and exclusion criteria. Two groups were made. Group A was treated with oral Zinc (10mg for <6 months old, 20mg for >6 months old for 14 days); low osmolarity Oral rehydration salt by 5 ml/kg per hour and continuation of nutritious feeding. Group B was treated with 250mg twice daily Sacchromyces boulardii along with oral Zinc (10mg for <6months old, 20mg for >6 months old for 14 days); low osmolarity Oral rehydration salt by 5 ml/kg per hour and continuation of nutritious feeding. Assessment included anthropometric measurements, hydration status, daily frequency and consistency of stools. Baseline investigations were sent to Combined Military Hospital, Tarbela Laboratory. Data was recorded on a specially designed proforma. Results: Duration of diarrhea was significantly lower in children who were given Saccharomyces boulardii with Zinc as compared to children who were given Zinc alone. i.e., group-A (Zinc): 53.31 hrs vs. group-B (Zinc+ Saccharomyces boulardii): 36.37 hrs, p<0.001 Conclusion: Saccharomyces boulardii can be effectively used with Zinc to treat acute watery diarrhea in children less than five years of age as it significantly reduces mean duration of diarrhea.
format article
author Ali Raza
Muhammad Zahid
Ehsan Qadir
Nazir Ahmed Malik
Sohail Aslam
Kashif Siddique
author_facet Ali Raza
Muhammad Zahid
Ehsan Qadir
Nazir Ahmed Malik
Sohail Aslam
Kashif Siddique
author_sort Ali Raza
title COMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEA
title_short COMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEA
title_full COMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEA
title_fullStr COMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEA
title_full_unstemmed COMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEA
title_sort comparison of world health organization treatment for acute watery diarrhea in children with and without sacchromyces boulardii in terms of mean duration of diarrhea
publisher Army Medical College Rawalpindi
publishDate 2020
url https://doaj.org/article/451b3790030b4625b6a46a36cdcec12e
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