Surfactant protein A reduces TLR4 and inflammatory cytokine mRNA levels in neonatal mouse ileum

Abstract Levels of intestinal toll-like receptor 4 (TLR4) impact inflammation in the neonatal gastrointestinal tract. While surfactant protein A (SP-A) is known to regulate TLR4 in the lung, it also reduces intestinal damage, TLR4 and inflammation in an experimental model of necrotizing enterocoliti...

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Autores principales: Lidan Liu, Chaim Z. Aron, Cullen M. Grable, Adrian Robles, Xiangli Liu, Yuying Liu, Nicole Y. Fatheree, J. Marc Rhoads, Joseph L. Alcorn
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4526f4d850a34818833e4b1e3c4527cb
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