Structural and functional analysis of the symmetrical Type I restriction endonuclease R.EcoR124I(NT).

Type I restriction-modification (RM) systems are comprised of two multi-subunit enzymes, the methyltransferase (∼160 kDa), responsible for methylation of DNA, and the restriction endonuclease (∼400 kDa), responsible for DNA cleavage. Both enzymes share a number of subunits. An engineered RM system,...

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Autores principales: James E Taylor, Anna Swiderska, Jean-Baptiste Artero, Philip Callow, Geoff Kneale
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/4527021a2dd3489b9d5746d874fa7815
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