The mitotic kinesin-14 KlpA contains a context-dependent directionality switch

Kinesin-14s are commonly considered to be minus end-directed microtubule motor proteins. Here the authors show that KlpA, a fungal kinesin-14 orthologue, relies on its N-terminal nonmotor microtubule-binding tail to achieve context-dependent bidirectional motility.

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Autores principales:	Andrew R. Popchock, Kuo-Fu Tseng, Pan Wang, P. Andrew Karplus, Xin Xiang, Weihong Qiu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/452fe2c9c270404e86830743dc6002c8
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id	oai:doaj.org-article:452fe2c9c270404e86830743dc6002c8
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spelling	oai:doaj.org-article:452fe2c9c270404e86830743dc6002c82021-12-02T17:01:24ZThe mitotic kinesin-14 KlpA contains a context-dependent directionality switch10.1038/ncomms139992041-1723https://doaj.org/article/452fe2c9c270404e86830743dc6002c82017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms13999https://doaj.org/toc/2041-1723Kinesin-14s are commonly considered to be minus end-directed microtubule motor proteins. Here the authors show that KlpA, a fungal kinesin-14 orthologue, relies on its N-terminal nonmotor microtubule-binding tail to achieve context-dependent bidirectional motility.Andrew R. PopchockKuo-Fu TsengPan WangP. Andrew KarplusXin XiangWeihong QiuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Andrew R. Popchock Kuo-Fu Tseng Pan Wang P. Andrew Karplus Xin Xiang Weihong Qiu The mitotic kinesin-14 KlpA contains a context-dependent directionality switch
description	Kinesin-14s are commonly considered to be minus end-directed microtubule motor proteins. Here the authors show that KlpA, a fungal kinesin-14 orthologue, relies on its N-terminal nonmotor microtubule-binding tail to achieve context-dependent bidirectional motility.
format	article
author	Andrew R. Popchock Kuo-Fu Tseng Pan Wang P. Andrew Karplus Xin Xiang Weihong Qiu
author_facet	Andrew R. Popchock Kuo-Fu Tseng Pan Wang P. Andrew Karplus Xin Xiang Weihong Qiu
author_sort	Andrew R. Popchock
title	The mitotic kinesin-14 KlpA contains a context-dependent directionality switch
title_short	The mitotic kinesin-14 KlpA contains a context-dependent directionality switch
title_full	The mitotic kinesin-14 KlpA contains a context-dependent directionality switch
title_fullStr	The mitotic kinesin-14 KlpA contains a context-dependent directionality switch
title_full_unstemmed	The mitotic kinesin-14 KlpA contains a context-dependent directionality switch
title_sort	mitotic kinesin-14 klpa contains a context-dependent directionality switch
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/452fe2c9c270404e86830743dc6002c8
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The mitotic kinesin-14 KlpA contains a context-dependent directionality switch

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