USE OF BIOPROSTHESIS WITH EXTERNAL SUPPORT BY KNITTED NITINOL MESH AS A CONDUIT IN INFRAINGUINAL BYPASS SURGERY: RANDOMIZED CONTROLLED TRIAL

Background. Autovein is considered as the best prosthesis in the infrainguinal bypass surgery. However, in 30 % of individuals great saphenous vein is inappropriate for grafting because it is too small or due to phlebitis, varicosity and prior surgery. From this point of view, decellularized vascula...

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Autores principales: A. O. Ivchenko, A. N. Shvedov, O. A. Ivchenko, I. O. Savelyev
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Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2017
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spelling oai:doaj.org-article:453a45cc0e0b4698a5646238687e780d2021-11-23T06:14:39ZUSE OF BIOPROSTHESIS WITH EXTERNAL SUPPORT BY KNITTED NITINOL MESH AS A CONDUIT IN INFRAINGUINAL BYPASS SURGERY: RANDOMIZED CONTROLLED TRIAL2541-94202587-959610.12737/article_5a0a8a77c92410.82422845https://doaj.org/article/453a45cc0e0b4698a5646238687e780d2017-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/480https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Background. Autovein is considered as the best prosthesis in the infrainguinal bypass surgery. However, in 30 % of individuals great saphenous vein is inappropriate for grafting because it is too small or due to phlebitis, varicosity and prior surgery. From this point of view, decellularized vascular grafts, which retain most of the properties of living tissues, seem quite interesting. Due to the high frequency of development of prosthetic aneurysm in the postoperative period xenografts does not gain high popularity. This complication occurs in an average of 6 % of cases, but modern technological advances in manufacture of xenografts have reduced the percentage of aneurysms to 4.1 %, which is still high. To solve this problem, we decided to use external support of nitinol mesh. Aim: assessment of efficiency of bioprosthesis with external support by knitted nitinol mesh as a conduit in infrainguinal bypass surgery. Materials and methods. It was a single-center randomized controlled trial in two groups, 36 patients in each group. There were no statistically significant differences between the groups. Patients of the control group underwent a standard femoropopliteal bypass surgery. In experimental group we used bioprosthesis with external support by knitted nitinol mesh. Results. Aneurysms development was observed in 6 patients (16.67 %) of the control group (4 patients - anastomotic aneurysms; 2 patients - true shunt aneurysms). There were no aneurysms in the experimental group (p < 0.05). Conclusion. The use of a nitinol-based mesh effectively prevents the development of an aneurysm of the xenograft in the postoperative period.A. O. IvchenkoA. N. ShvedovO. A. IvchenkoI. O. SavelyevScientific Сentre for Family Health and Human Reproduction Problemsarticlexenoprothesistitanium nickelideextravasal constructionreinforced xenoprothesisxenoprothesis with external supportnitinolaneurysmScienceQRUActa Biomedica Scientifica, Vol 2, Iss 6, Pp 114-117 (2017)
institution DOAJ
collection DOAJ
language RU
topic xenoprothesis
titanium nickelide
extravasal construction
reinforced xenoprothesis
xenoprothesis with external support
nitinol
aneurysm
Science
Q
spellingShingle xenoprothesis
titanium nickelide
extravasal construction
reinforced xenoprothesis
xenoprothesis with external support
nitinol
aneurysm
Science
Q
A. O. Ivchenko
A. N. Shvedov
O. A. Ivchenko
I. O. Savelyev
USE OF BIOPROSTHESIS WITH EXTERNAL SUPPORT BY KNITTED NITINOL MESH AS A CONDUIT IN INFRAINGUINAL BYPASS SURGERY: RANDOMIZED CONTROLLED TRIAL
description Background. Autovein is considered as the best prosthesis in the infrainguinal bypass surgery. However, in 30 % of individuals great saphenous vein is inappropriate for grafting because it is too small or due to phlebitis, varicosity and prior surgery. From this point of view, decellularized vascular grafts, which retain most of the properties of living tissues, seem quite interesting. Due to the high frequency of development of prosthetic aneurysm in the postoperative period xenografts does not gain high popularity. This complication occurs in an average of 6 % of cases, but modern technological advances in manufacture of xenografts have reduced the percentage of aneurysms to 4.1 %, which is still high. To solve this problem, we decided to use external support of nitinol mesh. Aim: assessment of efficiency of bioprosthesis with external support by knitted nitinol mesh as a conduit in infrainguinal bypass surgery. Materials and methods. It was a single-center randomized controlled trial in two groups, 36 patients in each group. There were no statistically significant differences between the groups. Patients of the control group underwent a standard femoropopliteal bypass surgery. In experimental group we used bioprosthesis with external support by knitted nitinol mesh. Results. Aneurysms development was observed in 6 patients (16.67 %) of the control group (4 patients - anastomotic aneurysms; 2 patients - true shunt aneurysms). There were no aneurysms in the experimental group (p < 0.05). Conclusion. The use of a nitinol-based mesh effectively prevents the development of an aneurysm of the xenograft in the postoperative period.
format article
author A. O. Ivchenko
A. N. Shvedov
O. A. Ivchenko
I. O. Savelyev
author_facet A. O. Ivchenko
A. N. Shvedov
O. A. Ivchenko
I. O. Savelyev
author_sort A. O. Ivchenko
title USE OF BIOPROSTHESIS WITH EXTERNAL SUPPORT BY KNITTED NITINOL MESH AS A CONDUIT IN INFRAINGUINAL BYPASS SURGERY: RANDOMIZED CONTROLLED TRIAL
title_short USE OF BIOPROSTHESIS WITH EXTERNAL SUPPORT BY KNITTED NITINOL MESH AS A CONDUIT IN INFRAINGUINAL BYPASS SURGERY: RANDOMIZED CONTROLLED TRIAL
title_full USE OF BIOPROSTHESIS WITH EXTERNAL SUPPORT BY KNITTED NITINOL MESH AS A CONDUIT IN INFRAINGUINAL BYPASS SURGERY: RANDOMIZED CONTROLLED TRIAL
title_fullStr USE OF BIOPROSTHESIS WITH EXTERNAL SUPPORT BY KNITTED NITINOL MESH AS A CONDUIT IN INFRAINGUINAL BYPASS SURGERY: RANDOMIZED CONTROLLED TRIAL
title_full_unstemmed USE OF BIOPROSTHESIS WITH EXTERNAL SUPPORT BY KNITTED NITINOL MESH AS A CONDUIT IN INFRAINGUINAL BYPASS SURGERY: RANDOMIZED CONTROLLED TRIAL
title_sort use of bioprosthesis with external support by knitted nitinol mesh as a conduit in infrainguinal bypass surgery: randomized controlled trial
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2017
url https://doaj.org/article/453a45cc0e0b4698a5646238687e780d
work_keys_str_mv AT aoivchenko useofbioprosthesiswithexternalsupportbyknittednitinolmeshasaconduitininfrainguinalbypasssurgeryrandomizedcontrolledtrial
AT anshvedov useofbioprosthesiswithexternalsupportbyknittednitinolmeshasaconduitininfrainguinalbypasssurgeryrandomizedcontrolledtrial
AT oaivchenko useofbioprosthesiswithexternalsupportbyknittednitinolmeshasaconduitininfrainguinalbypasssurgeryrandomizedcontrolledtrial
AT iosavelyev useofbioprosthesiswithexternalsupportbyknittednitinolmeshasaconduitininfrainguinalbypasssurgeryrandomizedcontrolledtrial
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