EPIDEMIOLOGIC CHARACTERISTICS AND IMMUNOLOGICAL ASPECTS OF PRENATAL INFECTION

Abstract. To improve diagnostics of prenatal infections the basic obstetrics indices in Omsk region in the period of 2000–2010 years have been analyzed. It was found that perinatal mortality reduced 2.5 times (from 14.5 till 5.7 per 1000 newborns) as well as neonatal mortality (from 6.5 till 0.9 per...

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Autores principales:	T. I. Dolgih, M. V. Shelev, J. I. Tirskaya, T. N. Belkova
Formato:	article
Lenguaje:	RU
Publicado:	Sankt-Peterburg : NIIÈM imeni Pastera 2014
Materias:	epidemiology newborns prenatal infection lymphocytes cytokines Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/453eccdb08bd42e684177d20b61acde7
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spelling	oai:doaj.org-article:453eccdb08bd42e684177d20b61acde72021-11-22T07:09:45ZEPIDEMIOLOGIC CHARACTERISTICS AND IMMUNOLOGICAL ASPECTS OF PRENATAL INFECTION2220-76192313-739810.15789/2220-7619-2012-3-651-656https://doaj.org/article/453eccdb08bd42e684177d20b61acde72014-07-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/81https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Abstract. To improve diagnostics of prenatal infections the basic obstetrics indices in Omsk region in the period of 2000–2010 years have been analyzed. It was found that perinatal mortality reduced 2.5 times (from 14.5 till 5.7 per 1000 newborns) as well as neonatal mortality (from 6.5 till 0.9 per 1000 newborns). The laboratory testing of 187 newborns (85 pairs mother-newborn) revealed monoinfection in 24% of cases and mixed infection in 7% of cases with predomination of herpes viruses (HHV-6, CMV, EBV, HSV1,2). Newborns with manifested infections had increased number of cytotoxic T-cells, intensive expression of HLA-DR antigens on monocytes and IL-8 chemokine increased production.T. I. DolgihM. V. ShelevJ. I. TirskayaT. N. BelkovaSankt-Peterburg : NIIÈM imeni Pasteraarticleepidemiologynewbornsprenatal infectionlymphocytescytokinesInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 2, Iss 3, Pp 651-656 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	epidemiology newborns prenatal infection lymphocytes cytokines Infectious and parasitic diseases RC109-216
spellingShingle	epidemiology newborns prenatal infection lymphocytes cytokines Infectious and parasitic diseases RC109-216 T. I. Dolgih M. V. Shelev J. I. Tirskaya T. N. Belkova EPIDEMIOLOGIC CHARACTERISTICS AND IMMUNOLOGICAL ASPECTS OF PRENATAL INFECTION
description	Abstract. To improve diagnostics of prenatal infections the basic obstetrics indices in Omsk region in the period of 2000–2010 years have been analyzed. It was found that perinatal mortality reduced 2.5 times (from 14.5 till 5.7 per 1000 newborns) as well as neonatal mortality (from 6.5 till 0.9 per 1000 newborns). The laboratory testing of 187 newborns (85 pairs mother-newborn) revealed monoinfection in 24% of cases and mixed infection in 7% of cases with predomination of herpes viruses (HHV-6, CMV, EBV, HSV1,2). Newborns with manifested infections had increased number of cytotoxic T-cells, intensive expression of HLA-DR antigens on monocytes and IL-8 chemokine increased production.
format	article
author	T. I. Dolgih M. V. Shelev J. I. Tirskaya T. N. Belkova
author_facet	T. I. Dolgih M. V. Shelev J. I. Tirskaya T. N. Belkova
author_sort	T. I. Dolgih
title	EPIDEMIOLOGIC CHARACTERISTICS AND IMMUNOLOGICAL ASPECTS OF PRENATAL INFECTION
title_short	EPIDEMIOLOGIC CHARACTERISTICS AND IMMUNOLOGICAL ASPECTS OF PRENATAL INFECTION
title_full	EPIDEMIOLOGIC CHARACTERISTICS AND IMMUNOLOGICAL ASPECTS OF PRENATAL INFECTION
title_fullStr	EPIDEMIOLOGIC CHARACTERISTICS AND IMMUNOLOGICAL ASPECTS OF PRENATAL INFECTION
title_full_unstemmed	EPIDEMIOLOGIC CHARACTERISTICS AND IMMUNOLOGICAL ASPECTS OF PRENATAL INFECTION
title_sort	epidemiologic characteristics and immunological aspects of prenatal infection
publisher	Sankt-Peterburg : NIIÈM imeni Pastera
publishDate	2014
url	https://doaj.org/article/453eccdb08bd42e684177d20b61acde7
work_keys_str_mv	AT tidolgih epidemiologiccharacteristicsandimmunologicalaspectsofprenatalinfection AT mvshelev epidemiologiccharacteristicsandimmunologicalaspectsofprenatalinfection AT jitirskaya epidemiologiccharacteristicsandimmunologicalaspectsofprenatalinfection AT tnbelkova epidemiologiccharacteristicsandimmunologicalaspectsofprenatalinfection
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EPIDEMIOLOGIC CHARACTERISTICS AND IMMUNOLOGICAL ASPECTS OF PRENATAL INFECTION

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