Repeatability of automated measurements by a new anterior segment optical coherence tomographer and biometer and agreement with standard devices

Abstract We assess repeatability of automatic measurements of a new anterior segment optical coherence tomographer and biometer (ANTERION) and their agreement with those provided by an anterior segment-optical coherence tomography device combined with Placido-disk corneal topography (MS-39) and a va...

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Autores principales:	Domenico Schiano-Lomoriello, Kenneth J. Hoffer, Irene Abicca, Giacomo Savini
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4546be9eaaaa44afa12a178d081b742d
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spelling	oai:doaj.org-article:4546be9eaaaa44afa12a178d081b742d2021-12-02T14:01:33ZRepeatability of automated measurements by a new anterior segment optical coherence tomographer and biometer and agreement with standard devices10.1038/s41598-020-79674-42045-2322https://doaj.org/article/4546be9eaaaa44afa12a178d081b742d2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-79674-4https://doaj.org/toc/2045-2322Abstract We assess repeatability of automatic measurements of a new anterior segment optical coherence tomographer and biometer (ANTERION) and their agreement with those provided by an anterior segment-optical coherence tomography device combined with Placido-disk corneal topography (MS-39) and a validated optical biometer (IOLMaster 500). A consecutive series of patients underwent three measurements with ANTERION and one with MS-39. A subgroup of patients underwent biometry also with IOLMaster 500. Repeatability was assessed by means of within-subject standard deviation, coefficient of variation (COV), and intraclass correlation coefficient (ICC). Agreement was investigated with the 95% limits of agreement. Paired t-test and Wilcoxon matched-pairs test were performed to compare the measurements of the different devices. Repeatability of ANTERION measurements was high, with ICC > 0.98 for all parameters except astigmatism (0.963); all parameters apart from those related to astigmatism revealed a COV < 1%. Repeatability of astigmatism improved when only eyes whose keratometric astigmatism was higher than 1.0 D were investigated. Most measurements by ANTERION and MS-39 showed good agreement. No significant differences were found between measurements by ANTERION and IOLMaster, but for corneal diameter. ANTERION revealed high repeatability of automatic measurements and good agreement with both MS-39 and IOLMaster for most parameters.Domenico Schiano-LomorielloKenneth J. HofferIrene AbiccaGiacomo SaviniNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Domenico Schiano-Lomoriello Kenneth J. Hoffer Irene Abicca Giacomo Savini Repeatability of automated measurements by a new anterior segment optical coherence tomographer and biometer and agreement with standard devices
description	Abstract We assess repeatability of automatic measurements of a new anterior segment optical coherence tomographer and biometer (ANTERION) and their agreement with those provided by an anterior segment-optical coherence tomography device combined with Placido-disk corneal topography (MS-39) and a validated optical biometer (IOLMaster 500). A consecutive series of patients underwent three measurements with ANTERION and one with MS-39. A subgroup of patients underwent biometry also with IOLMaster 500. Repeatability was assessed by means of within-subject standard deviation, coefficient of variation (COV), and intraclass correlation coefficient (ICC). Agreement was investigated with the 95% limits of agreement. Paired t-test and Wilcoxon matched-pairs test were performed to compare the measurements of the different devices. Repeatability of ANTERION measurements was high, with ICC > 0.98 for all parameters except astigmatism (0.963); all parameters apart from those related to astigmatism revealed a COV < 1%. Repeatability of astigmatism improved when only eyes whose keratometric astigmatism was higher than 1.0 D were investigated. Most measurements by ANTERION and MS-39 showed good agreement. No significant differences were found between measurements by ANTERION and IOLMaster, but for corneal diameter. ANTERION revealed high repeatability of automatic measurements and good agreement with both MS-39 and IOLMaster for most parameters.
format	article
author	Domenico Schiano-Lomoriello Kenneth J. Hoffer Irene Abicca Giacomo Savini
author_facet	Domenico Schiano-Lomoriello Kenneth J. Hoffer Irene Abicca Giacomo Savini
author_sort	Domenico Schiano-Lomoriello
title	Repeatability of automated measurements by a new anterior segment optical coherence tomographer and biometer and agreement with standard devices
title_short	Repeatability of automated measurements by a new anterior segment optical coherence tomographer and biometer and agreement with standard devices
title_full	Repeatability of automated measurements by a new anterior segment optical coherence tomographer and biometer and agreement with standard devices
title_fullStr	Repeatability of automated measurements by a new anterior segment optical coherence tomographer and biometer and agreement with standard devices
title_full_unstemmed	Repeatability of automated measurements by a new anterior segment optical coherence tomographer and biometer and agreement with standard devices
title_sort	repeatability of automated measurements by a new anterior segment optical coherence tomographer and biometer and agreement with standard devices
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4546be9eaaaa44afa12a178d081b742d
work_keys_str_mv	AT domenicoschianolomoriello repeatabilityofautomatedmeasurementsbyanewanteriorsegmentopticalcoherencetomographerandbiometerandagreementwithstandarddevices AT kennethjhoffer repeatabilityofautomatedmeasurementsbyanewanteriorsegmentopticalcoherencetomographerandbiometerandagreementwithstandarddevices AT ireneabicca repeatabilityofautomatedmeasurementsbyanewanteriorsegmentopticalcoherencetomographerandbiometerandagreementwithstandarddevices AT giacomosavini repeatabilityofautomatedmeasurementsbyanewanteriorsegmentopticalcoherencetomographerandbiometerandagreementwithstandarddevices
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Repeatability of automated measurements by a new anterior segment optical coherence tomographer and biometer and agreement with standard devices

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