Lipopolysaccharide-affinity copolymer senses the rapid motility of swarmer bacteria to trigger antimicrobial drug release

Urinary tract infections are a common side effect of urethral catheters. Here, the authors report on the development of antibiotic loaded NPs with functional polymer coatings which attach too and are removed by motile bacteria to trigger the release of antibiotic.

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Autores principales: Shengtao Lu, Wuguo Bi, Quanchao Du, Sheetal Sinha, Xiangyang Wu, Arnold Subrata, Surajit Bhattacharjya, Bengang Xing, Edwin K. L. Yeow
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/454a5fc53d3747e8ad8862395a5e7a63
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spelling oai:doaj.org-article:454a5fc53d3747e8ad8862395a5e7a632021-12-02T17:31:44ZLipopolysaccharide-affinity copolymer senses the rapid motility of swarmer bacteria to trigger antimicrobial drug release10.1038/s41467-018-06729-62041-1723https://doaj.org/article/454a5fc53d3747e8ad8862395a5e7a632018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06729-6https://doaj.org/toc/2041-1723Urinary tract infections are a common side effect of urethral catheters. Here, the authors report on the development of antibiotic loaded NPs with functional polymer coatings which attach too and are removed by motile bacteria to trigger the release of antibiotic.Shengtao LuWuguo BiQuanchao DuSheetal SinhaXiangyang WuArnold SubrataSurajit BhattacharjyaBengang XingEdwin K. L. YeowNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shengtao Lu
Wuguo Bi
Quanchao Du
Sheetal Sinha
Xiangyang Wu
Arnold Subrata
Surajit Bhattacharjya
Bengang Xing
Edwin K. L. Yeow
Lipopolysaccharide-affinity copolymer senses the rapid motility of swarmer bacteria to trigger antimicrobial drug release
description Urinary tract infections are a common side effect of urethral catheters. Here, the authors report on the development of antibiotic loaded NPs with functional polymer coatings which attach too and are removed by motile bacteria to trigger the release of antibiotic.
format article
author Shengtao Lu
Wuguo Bi
Quanchao Du
Sheetal Sinha
Xiangyang Wu
Arnold Subrata
Surajit Bhattacharjya
Bengang Xing
Edwin K. L. Yeow
author_facet Shengtao Lu
Wuguo Bi
Quanchao Du
Sheetal Sinha
Xiangyang Wu
Arnold Subrata
Surajit Bhattacharjya
Bengang Xing
Edwin K. L. Yeow
author_sort Shengtao Lu
title Lipopolysaccharide-affinity copolymer senses the rapid motility of swarmer bacteria to trigger antimicrobial drug release
title_short Lipopolysaccharide-affinity copolymer senses the rapid motility of swarmer bacteria to trigger antimicrobial drug release
title_full Lipopolysaccharide-affinity copolymer senses the rapid motility of swarmer bacteria to trigger antimicrobial drug release
title_fullStr Lipopolysaccharide-affinity copolymer senses the rapid motility of swarmer bacteria to trigger antimicrobial drug release
title_full_unstemmed Lipopolysaccharide-affinity copolymer senses the rapid motility of swarmer bacteria to trigger antimicrobial drug release
title_sort lipopolysaccharide-affinity copolymer senses the rapid motility of swarmer bacteria to trigger antimicrobial drug release
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/454a5fc53d3747e8ad8862395a5e7a63
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