Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk

Mammographic density represents one the strongest predictors of breast cancer risk. Here the authors perform genome-wide association study meta-analysis of women screened with full-field digital mammography and identify 31 previously unreported loci associated with mammographic density phenotypes.

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Autores principales: Weiva Sieh, Joseph H. Rothstein, Robert J. Klein, Stacey E. Alexeeff, Lori C. Sakoda, Eric Jorgenson, Russell B. McBride, Rebecca E. Graff, Valerie McGuire, Ninah Achacoso, Luana Acton, Rhea Y. Liang, Jafi A. Lipson, Daniel L. Rubin, Martin J. Yaffe, Douglas F. Easton, Catherine Schaefer, Neil Risch, Alice S. Whittemore, Laurel A. Habel
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/455a1267540b4504a0c8a2bad60954fb
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spelling oai:doaj.org-article:455a1267540b4504a0c8a2bad60954fb2021-12-02T16:56:48ZIdentification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk10.1038/s41467-020-18883-x2041-1723https://doaj.org/article/455a1267540b4504a0c8a2bad60954fb2020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18883-xhttps://doaj.org/toc/2041-1723Mammographic density represents one the strongest predictors of breast cancer risk. Here the authors perform genome-wide association study meta-analysis of women screened with full-field digital mammography and identify 31 previously unreported loci associated with mammographic density phenotypes.Weiva SiehJoseph H. RothsteinRobert J. KleinStacey E. AlexeeffLori C. SakodaEric JorgensonRussell B. McBrideRebecca E. GraffValerie McGuireNinah AchacosoLuana ActonRhea Y. LiangJafi A. LipsonDaniel L. RubinMartin J. YaffeDouglas F. EastonCatherine SchaeferNeil RischAlice S. WhittemoreLaurel A. HabelNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Weiva Sieh
Joseph H. Rothstein
Robert J. Klein
Stacey E. Alexeeff
Lori C. Sakoda
Eric Jorgenson
Russell B. McBride
Rebecca E. Graff
Valerie McGuire
Ninah Achacoso
Luana Acton
Rhea Y. Liang
Jafi A. Lipson
Daniel L. Rubin
Martin J. Yaffe
Douglas F. Easton
Catherine Schaefer
Neil Risch
Alice S. Whittemore
Laurel A. Habel
Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk
description Mammographic density represents one the strongest predictors of breast cancer risk. Here the authors perform genome-wide association study meta-analysis of women screened with full-field digital mammography and identify 31 previously unreported loci associated with mammographic density phenotypes.
format article
author Weiva Sieh
Joseph H. Rothstein
Robert J. Klein
Stacey E. Alexeeff
Lori C. Sakoda
Eric Jorgenson
Russell B. McBride
Rebecca E. Graff
Valerie McGuire
Ninah Achacoso
Luana Acton
Rhea Y. Liang
Jafi A. Lipson
Daniel L. Rubin
Martin J. Yaffe
Douglas F. Easton
Catherine Schaefer
Neil Risch
Alice S. Whittemore
Laurel A. Habel
author_facet Weiva Sieh
Joseph H. Rothstein
Robert J. Klein
Stacey E. Alexeeff
Lori C. Sakoda
Eric Jorgenson
Russell B. McBride
Rebecca E. Graff
Valerie McGuire
Ninah Achacoso
Luana Acton
Rhea Y. Liang
Jafi A. Lipson
Daniel L. Rubin
Martin J. Yaffe
Douglas F. Easton
Catherine Schaefer
Neil Risch
Alice S. Whittemore
Laurel A. Habel
author_sort Weiva Sieh
title Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk
title_short Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk
title_full Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk
title_fullStr Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk
title_full_unstemmed Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk
title_sort identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/455a1267540b4504a0c8a2bad60954fb
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