Selective prebiotic conversion of pyrimidine and purine anhydronucleosides into Watson-Crick base-pairing arabino-furanosyl nucleosides in water

Arabinonucleic acid (ANA) Watson-Crick base-pair with RNA/DNA and can evolve to display enzyme-like function. Here, the authors now identify a prebiotic pathway that yields the complete set of Watson-Crick base-pairing purine and pyrimidine ANA nucleosides.

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Detalles Bibliográficos
Autores principales: Samuel J. Roberts, Rafał Szabla, Zoe R. Todd, Shaun Stairs, Dejan-Krešimir Bučar, Jiří Šponer, Dimitar D. Sasselov, Matthew W. Powner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/455de6701d6f41b6b2ff842b73e5e635
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Sumario:Arabinonucleic acid (ANA) Watson-Crick base-pair with RNA/DNA and can evolve to display enzyme-like function. Here, the authors now identify a prebiotic pathway that yields the complete set of Watson-Crick base-pairing purine and pyrimidine ANA nucleosides.