Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes

Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes

Interneurons in the neocortex have functional and morphological subtypes. Here, Mariotti and colleagues show that activation of parvalbumin-expressing interneurons evokes depressing calcium responses in astrocytes while somatostatin-expressing interneurons evoke potentiating astrocytic responses.

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Detalles Bibliográficos
Autores principales: Letizia Mariotti, Gabriele Losi, Annamaria Lia, Marcello Melone, Angela Chiavegato, Marta Gómez-Gonzalo, Michele Sessolo, Serena Bovetti, Angelo Forli, Micaela Zonta, Linda Maria Requie, Iacopo Marcon, Arianna Pugliese, Cécile Viollet, Bernhard Bettler, Tommaso Fellin, Fiorenzo Conti, Giorgio Carmignoto
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/456179a2c5a54300b6477423f829937e
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Descripción
Sumario:Interneurons in the neocortex have functional and morphological subtypes. Here, Mariotti and colleagues show that activation of parvalbumin-expressing interneurons evokes depressing calcium responses in astrocytes while somatostatin-expressing interneurons evoke potentiating astrocytic responses.

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