Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes
Interneurons in the neocortex have functional and morphological subtypes. Here, Mariotti and colleagues show that activation of parvalbumin-expressing interneurons evokes depressing calcium responses in astrocytes while somatostatin-expressing interneurons evoke potentiating astrocytic responses.
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Nature Portfolio
2018
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oai:doaj.org-article:456179a2c5a54300b6477423f829937e2021-12-02T17:32:31ZInterneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes10.1038/s41467-017-02642-62041-1723https://doaj.org/article/456179a2c5a54300b6477423f829937e2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02642-6https://doaj.org/toc/2041-1723Interneurons in the neocortex have functional and morphological subtypes. Here, Mariotti and colleagues show that activation of parvalbumin-expressing interneurons evokes depressing calcium responses in astrocytes while somatostatin-expressing interneurons evoke potentiating astrocytic responses.Letizia MariottiGabriele LosiAnnamaria LiaMarcello MeloneAngela ChiavegatoMarta Gómez-GonzaloMichele SessoloSerena BovettiAngelo ForliMicaela ZontaLinda Maria RequieIacopo MarconArianna PuglieseCécile ViolletBernhard BettlerTommaso FellinFiorenzo ContiGiorgio CarmignotoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
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DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
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Science Q Letizia Mariotti Gabriele Losi Annamaria Lia Marcello Melone Angela Chiavegato Marta Gómez-Gonzalo Michele Sessolo Serena Bovetti Angelo Forli Micaela Zonta Linda Maria Requie Iacopo Marcon Arianna Pugliese Cécile Viollet Bernhard Bettler Tommaso Fellin Fiorenzo Conti Giorgio Carmignoto Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes |
| description |
Interneurons in the neocortex have functional and morphological subtypes. Here, Mariotti and colleagues show that activation of parvalbumin-expressing interneurons evokes depressing calcium responses in astrocytes while somatostatin-expressing interneurons evoke potentiating astrocytic responses. |
| format |
article |
| author |
Letizia Mariotti Gabriele Losi Annamaria Lia Marcello Melone Angela Chiavegato Marta Gómez-Gonzalo Michele Sessolo Serena Bovetti Angelo Forli Micaela Zonta Linda Maria Requie Iacopo Marcon Arianna Pugliese Cécile Viollet Bernhard Bettler Tommaso Fellin Fiorenzo Conti Giorgio Carmignoto |
| author_facet |
Letizia Mariotti Gabriele Losi Annamaria Lia Marcello Melone Angela Chiavegato Marta Gómez-Gonzalo Michele Sessolo Serena Bovetti Angelo Forli Micaela Zonta Linda Maria Requie Iacopo Marcon Arianna Pugliese Cécile Viollet Bernhard Bettler Tommaso Fellin Fiorenzo Conti Giorgio Carmignoto |
| author_sort |
Letizia Mariotti |
| title |
Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes |
| title_short |
Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes |
| title_full |
Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes |
| title_fullStr |
Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes |
| title_full_unstemmed |
Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes |
| title_sort |
interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/456179a2c5a54300b6477423f829937e |
| work_keys_str_mv |
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1718380244240433152 |