Middle east pain syndrome is a pollution-induced new disease mimicking rheumatoid arthritis

Abstract Musculoskeletal pains are sometimes misdiagnosed in some diseases, like rheumatoid and psoriatic arthritis, erosive OA, etc. Secondary hyperparathyroidism was not considered a differential diagnosis for RA, despite the fact that it can cause arthralgia or arthritis. Also, fibromyalgia is a...

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Autores principales:	Adel A. Elbeialy, Abdlnby M. Bauomi, Basma M. Elnaggar, Hala M. Elzomor
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/456e10a21f034fe3bd01d61934cee328
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spelling	oai:doaj.org-article:456e10a21f034fe3bd01d61934cee3282021-11-21T12:25:13ZMiddle east pain syndrome is a pollution-induced new disease mimicking rheumatoid arthritis10.1038/s41598-021-01698-12045-2322https://doaj.org/article/456e10a21f034fe3bd01d61934cee3282021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-01698-1https://doaj.org/toc/2045-2322Abstract Musculoskeletal pains are sometimes misdiagnosed in some diseases, like rheumatoid and psoriatic arthritis, erosive OA, etc. Secondary hyperparathyroidism was not considered a differential diagnosis for RA, despite the fact that it can cause arthralgia or arthritis. Also, fibromyalgia is a psychosomatic condition marked by widespread pain and tenderness. This study included 400 patients attended certain outpatient clinics of Rheumatology in Egypt and Saudi Arabia, who were not fulfilling criteria for RA diagnosis. Criteria for classification of fibromyalgia syndrome were applied to all patients. We did lab tests and radiological imaging modalities for diagnosis or exclusion of suspected diseases were applied. All patients were fulfilling both old and new criteria of fibromyalgia syndrome, and not fulfilling any RA criteria, and had vitamin D3 deficiency or insufficiency. 75% of patients had abnormally high levels of PTH, without parathyroid gland pathology. Radiology showed subperiosteal and subchondral resorption of mainly thumbs, subchondral osteopenia of proximal and middle phalanges, mild subperiosteal resorption along the radial aspect of the middle phalanx and mild tuft erosions, besides changes in the carpus closely resembling those of rheumatoid arthritis, of ulnar styloid resorption, radiocarpal and scapho-trapezoid joint arthritis. Of special interest, the presence of tuft spur-like excrescences.Adel A. ElbeialyAbdlnby M. BauomiBasma M. ElnaggarHala M. ElzomorNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Adel A. Elbeialy Abdlnby M. Bauomi Basma M. Elnaggar Hala M. Elzomor Middle east pain syndrome is a pollution-induced new disease mimicking rheumatoid arthritis
description	Abstract Musculoskeletal pains are sometimes misdiagnosed in some diseases, like rheumatoid and psoriatic arthritis, erosive OA, etc. Secondary hyperparathyroidism was not considered a differential diagnosis for RA, despite the fact that it can cause arthralgia or arthritis. Also, fibromyalgia is a psychosomatic condition marked by widespread pain and tenderness. This study included 400 patients attended certain outpatient clinics of Rheumatology in Egypt and Saudi Arabia, who were not fulfilling criteria for RA diagnosis. Criteria for classification of fibromyalgia syndrome were applied to all patients. We did lab tests and radiological imaging modalities for diagnosis or exclusion of suspected diseases were applied. All patients were fulfilling both old and new criteria of fibromyalgia syndrome, and not fulfilling any RA criteria, and had vitamin D3 deficiency or insufficiency. 75% of patients had abnormally high levels of PTH, without parathyroid gland pathology. Radiology showed subperiosteal and subchondral resorption of mainly thumbs, subchondral osteopenia of proximal and middle phalanges, mild subperiosteal resorption along the radial aspect of the middle phalanx and mild tuft erosions, besides changes in the carpus closely resembling those of rheumatoid arthritis, of ulnar styloid resorption, radiocarpal and scapho-trapezoid joint arthritis. Of special interest, the presence of tuft spur-like excrescences.
format	article
author	Adel A. Elbeialy Abdlnby M. Bauomi Basma M. Elnaggar Hala M. Elzomor
author_facet	Adel A. Elbeialy Abdlnby M. Bauomi Basma M. Elnaggar Hala M. Elzomor
author_sort	Adel A. Elbeialy
title	Middle east pain syndrome is a pollution-induced new disease mimicking rheumatoid arthritis
title_short	Middle east pain syndrome is a pollution-induced new disease mimicking rheumatoid arthritis
title_full	Middle east pain syndrome is a pollution-induced new disease mimicking rheumatoid arthritis
title_fullStr	Middle east pain syndrome is a pollution-induced new disease mimicking rheumatoid arthritis
title_full_unstemmed	Middle east pain syndrome is a pollution-induced new disease mimicking rheumatoid arthritis
title_sort	middle east pain syndrome is a pollution-induced new disease mimicking rheumatoid arthritis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/456e10a21f034fe3bd01d61934cee328
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Middle east pain syndrome is a pollution-induced new disease mimicking rheumatoid arthritis

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