RAD50 is required for efficient initiation of resection and recombinational repair at random, gamma-induced double-strand break ends.
Resection of DNA double-strand break (DSB) ends is generally considered a critical determinant in pathways of DSB repair and genome stability. Unlike for enzymatically induced site-specific DSBs, little is known about processing of random "dirty-ended" DSBs created by DNA damaging agents s...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2009
|
| Subjects: | |
| Online Access: | https://doaj.org/article/456e7452b8874470b01a8e61f3d54a07 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|