Adenoviral vectors stimulate glucagon transcription in human mesenchymal stem cells expressing pancreatic transcription factors.
Viral gene carriers are being widely used as gene transfer systems in (trans)differentiation and reprogramming strategies. Forced expression of key regulators of pancreatic differentiation in stem cells, liver cells, pancreatic duct cells, or cells from the exocrine pancreas, can lead to the initiat...
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Autores principales: | Arnaud Zaldumbide, Françoise Carlotti, Manuel A Gonçalves, Shoshan Knaän-Shanzer, Steve J Cramer, Bart O Roep, Emmanuel J H J Wiertz, Rob C Hoeben |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/457a7c07e9944d708545135dd0ecfe6e |
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