Noncytotoxic functions of killer cell granzymes in viral infections.
Cytotoxic lymphocytes produce granules armed with a set of 5 serine proteases (granzymes (Gzms)), which, together with the pore-forming protein (perforin), serve as a major defense against viral infections in humans. This granule-exocytosis pathway subsumes a well-established mechanism in which targ...
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Auteurs principaux: | Lisanne C de Jong, Sandra Crnko, Toine Ten Broeke, Niels Bovenschen |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2021
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Accès en ligne: | https://doaj.org/article/457ae3a589ce4f15a2f5f66d5c90e0e5 |
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