The journey of rheumatoid arthritis patients: a review of reported lag times from the onset of symptoms
Alaa S Barhamain,1 Rami F Magliah,1 Mohammad H Shaheen,1 Shurooq F Munassar,1 Ayman M Falemban,1 Mohammed M Alshareef,1 Hani M Almoallim1–3 1Department of Medicine, Faculty of Medicine, 2Alzaidi Chair of Research in Rheumatic Diseases, Umm Alqura University, Makkah, 3Department of Medicine...
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Dove Medical Press
2017
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oai:doaj.org-article:457eb48d90964ae2b9b5168dac11430c2021-12-02T05:04:18ZThe journey of rheumatoid arthritis patients: a review of reported lag times from the onset of symptoms1179-156Xhttps://doaj.org/article/457eb48d90964ae2b9b5168dac11430c2017-07-01T00:00:00Zhttps://www.dovepress.com/the-journey-of-rheumatoid-arthritis-patients-a-review-of-reported-lag--peer-reviewed-article-OARRRhttps://doaj.org/toc/1179-156XAlaa S Barhamain,1 Rami F Magliah,1 Mohammad H Shaheen,1 Shurooq F Munassar,1 Ayman M Falemban,1 Mohammed M Alshareef,1 Hani M Almoallim1–3 1Department of Medicine, Faculty of Medicine, 2Alzaidi Chair of Research in Rheumatic Diseases, Umm Alqura University, Makkah, 3Department of Medicine, Dr Soleiman Fakeeh Hospital, Jeddah, Saudi Arabia Background: Even after achieving tremendous advances in diagnosis and treatment of rheumatoid arthritis (RA), many of the patients undergo delays in diagnosis and initiation of treatment, which leads to worsening of the condition and poor prognosis. Objective: The objective of this study was to perform a literature review to quantify the lag times in diagnosis and treatment of RA and study the reported factors associated with it.Methods: The authors searched literature published until September 2016 in electronic full-text and abstract databases and hand-searched the suitable articles. Results: The weighted average of median lag time from symptom onset to therapy was 11.79 months (12 studies, 5,512 patients, range 3.6–24.0 months). Lag1 was 3.14 months (onset of symptoms to first physician consultant; 12 studies, 6,055 patients, range 0–5.7 months); lag2 was 2.13 months (physician visit to RA specialist referral; 13 studies, 34,767 patients, range 0.5–6.6 months); lag3 was 2.91 months (consultation with rheumatologist to diagnosis; 3 studies, 563 patients, range 0–5 months), lag4 was 2.14 months (diagnosis to initiation of disease-modifying antirheumatic drug therapy; 5 studies, 30,685 patients, range 0–2.2 months). Numerous patient- and physician-related factors like gender, ethnicity, primary care physician knowledge of the condition, availability of diagnostics, and so on were responsible for the delays.Conclusion: This review estimated the delay times and identified the main factors for delay in RA patients in diagnosis and initiation of treatment. A most plausible solution to this is coordinated effort by the rheumatology and primary care physicians. Keywords: arthritis, rheumatoid, rheumatologists, lag time, delay, diagnosis, disease managementBarhamain ASMagliah RFShaheen MHMunassar SFFalemban AMAlshareef MMAlmoallim HMDove Medical PressarticleArthritisRheumatoidrheumatologistslag timeDiagnosisDisease ManagementTherapeutics.Diseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol Volume 9, Pp 139-150 (2017) |
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DOAJ |
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Arthritis Rheumatoid rheumatologists lag time Diagnosis Disease Management Therapeutics. Diseases of the musculoskeletal system RC925-935 |
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Arthritis Rheumatoid rheumatologists lag time Diagnosis Disease Management Therapeutics. Diseases of the musculoskeletal system RC925-935 Barhamain AS Magliah RF Shaheen MH Munassar SF Falemban AM Alshareef MM Almoallim HM The journey of rheumatoid arthritis patients: a review of reported lag times from the onset of symptoms |
| description |
Alaa S Barhamain,1 Rami F Magliah,1 Mohammad H Shaheen,1 Shurooq F Munassar,1 Ayman M Falemban,1 Mohammed M Alshareef,1 Hani M Almoallim1–3 1Department of Medicine, Faculty of Medicine, 2Alzaidi Chair of Research in Rheumatic Diseases, Umm Alqura University, Makkah, 3Department of Medicine, Dr Soleiman Fakeeh Hospital, Jeddah, Saudi Arabia Background: Even after achieving tremendous advances in diagnosis and treatment of rheumatoid arthritis (RA), many of the patients undergo delays in diagnosis and initiation of treatment, which leads to worsening of the condition and poor prognosis. Objective: The objective of this study was to perform a literature review to quantify the lag times in diagnosis and treatment of RA and study the reported factors associated with it.Methods: The authors searched literature published until September 2016 in electronic full-text and abstract databases and hand-searched the suitable articles. Results: The weighted average of median lag time from symptom onset to therapy was 11.79 months (12 studies, 5,512 patients, range 3.6–24.0 months). Lag1 was 3.14 months (onset of symptoms to first physician consultant; 12 studies, 6,055 patients, range 0–5.7 months); lag2 was 2.13 months (physician visit to RA specialist referral; 13 studies, 34,767 patients, range 0.5–6.6 months); lag3 was 2.91 months (consultation with rheumatologist to diagnosis; 3 studies, 563 patients, range 0–5 months), lag4 was 2.14 months (diagnosis to initiation of disease-modifying antirheumatic drug therapy; 5 studies, 30,685 patients, range 0–2.2 months). Numerous patient- and physician-related factors like gender, ethnicity, primary care physician knowledge of the condition, availability of diagnostics, and so on were responsible for the delays.Conclusion: This review estimated the delay times and identified the main factors for delay in RA patients in diagnosis and initiation of treatment. A most plausible solution to this is coordinated effort by the rheumatology and primary care physicians. Keywords: arthritis, rheumatoid, rheumatologists, lag time, delay, diagnosis, disease management |
| format |
article |
| author |
Barhamain AS Magliah RF Shaheen MH Munassar SF Falemban AM Alshareef MM Almoallim HM |
| author_facet |
Barhamain AS Magliah RF Shaheen MH Munassar SF Falemban AM Alshareef MM Almoallim HM |
| author_sort |
Barhamain AS |
| title |
The journey of rheumatoid arthritis patients: a review of reported lag times from the onset of symptoms |
| title_short |
The journey of rheumatoid arthritis patients: a review of reported lag times from the onset of symptoms |
| title_full |
The journey of rheumatoid arthritis patients: a review of reported lag times from the onset of symptoms |
| title_fullStr |
The journey of rheumatoid arthritis patients: a review of reported lag times from the onset of symptoms |
| title_full_unstemmed |
The journey of rheumatoid arthritis patients: a review of reported lag times from the onset of symptoms |
| title_sort |
journey of rheumatoid arthritis patients: a review of reported lag times from the onset of symptoms |
| publisher |
Dove Medical Press |
| publishDate |
2017 |
| url |
https://doaj.org/article/457eb48d90964ae2b9b5168dac11430c |
| work_keys_str_mv |
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