TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine

Developmental cues for the different dendritic cell (DC) subsets in the intestine are yet to be defined. Here the authors show that TGFβR1 signalling is needed for development of CD103+CD11b+ intestinal DCs from CD103−CD11b+ cells and that they contribute to the generation of Th17 and regulatory T c...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	C. C. Bain, J. Montgomery, C. L. Scott, J. M. Kel, M. J. H. Girard-Madoux, L. Martens, T. F. P. Zangerle-Murray, J. Ober-Blöbaum, D. Lindenbergh-Kortleve, J. N. Samsom, S. Henri, T. Lawrence, Y. Saeys, B. Malissen, M. Dalod, B. E. Clausen, A. McI. Mowat
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4581ca774d5841c890557730e8ad8bd2
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:4581ca774d5841c890557730e8ad8bd2
record_format	dspace
spelling	oai:doaj.org-article:4581ca774d5841c890557730e8ad8bd22021-12-02T14:42:11ZTGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine10.1038/s41467-017-00658-62041-1723https://doaj.org/article/4581ca774d5841c890557730e8ad8bd22017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00658-6https://doaj.org/toc/2041-1723Developmental cues for the different dendritic cell (DC) subsets in the intestine are yet to be defined. Here the authors show that TGFβR1 signalling is needed for development of CD103+CD11b+ intestinal DCs from CD103−CD11b+ cells and that they contribute to the generation of Th17 and regulatory T cellsC. C. BainJ. MontgomeryC. L. ScottJ. M. KelM. J. H. Girard-MadouxL. MartensT. F. P. Zangerle-MurrayJ. Ober-BlöbaumD. Lindenbergh-KortleveJ. N. SamsomS. HenriT. LawrenceY. SaeysB. MalissenM. DalodB. E. ClausenA. McI. MowatNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q C. C. Bain J. Montgomery C. L. Scott J. M. Kel M. J. H. Girard-Madoux L. Martens T. F. P. Zangerle-Murray J. Ober-Blöbaum D. Lindenbergh-Kortleve J. N. Samsom S. Henri T. Lawrence Y. Saeys B. Malissen M. Dalod B. E. Clausen A. McI. Mowat TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine
description	Developmental cues for the different dendritic cell (DC) subsets in the intestine are yet to be defined. Here the authors show that TGFβR1 signalling is needed for development of CD103+CD11b+ intestinal DCs from CD103−CD11b+ cells and that they contribute to the generation of Th17 and regulatory T cells
format	article
author	C. C. Bain J. Montgomery C. L. Scott J. M. Kel M. J. H. Girard-Madoux L. Martens T. F. P. Zangerle-Murray J. Ober-Blöbaum D. Lindenbergh-Kortleve J. N. Samsom S. Henri T. Lawrence Y. Saeys B. Malissen M. Dalod B. E. Clausen A. McI. Mowat
author_facet	C. C. Bain J. Montgomery C. L. Scott J. M. Kel M. J. H. Girard-Madoux L. Martens T. F. P. Zangerle-Murray J. Ober-Blöbaum D. Lindenbergh-Kortleve J. N. Samsom S. Henri T. Lawrence Y. Saeys B. Malissen M. Dalod B. E. Clausen A. McI. Mowat
author_sort	C. C. Bain
title	TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine
title_short	TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine
title_full	TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine
title_fullStr	TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine
title_full_unstemmed	TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine
title_sort	tgfβr signalling controls cd103+cd11b+ dendritic cell development in the intestine
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/4581ca774d5841c890557730e8ad8bd2
work_keys_str_mv	AT ccbain tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT jmontgomery tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT clscott tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT jmkel tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT mjhgirardmadoux tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT lmartens tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT tfpzangerlemurray tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT joberblobaum tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT dlindenberghkortleve tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT jnsamsom tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT shenri tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT tlawrence tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT ysaeys tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT bmalissen tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT mdalod tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT beclausen tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine AT amcimowat tgfbrsignallingcontrolscd103cd11bdendriticcelldevelopmentintheintestine
_version_	1718389745972674560

TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine

Ejemplares similares