Perspectives on skeletal muscle stem cells

Skeletal muscle has a remarkable regenerative capacity, which can largely be attributed to resident muscle stem cells (MuSCs). Here, the authors review the molecular mechanisms regulating MuSC quiescence, activation and proliferation, how these processes are regulated by the stem cell niche, and the...

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Autores principales:	F. Relaix, M. Bencze, M. J. Borok, A. Der Vartanian, F. Gattazzo, D. Mademtzoglou, S. Perez-Diaz, A. Prola, P. C. Reyes-Fernandez, A. Rotini, Taglietti
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/458d5c3a713043e5bfa5170ab7c291af
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spelling	oai:doaj.org-article:458d5c3a713043e5bfa5170ab7c291af2021-12-02T14:16:13ZPerspectives on skeletal muscle stem cells10.1038/s41467-020-20760-62041-1723https://doaj.org/article/458d5c3a713043e5bfa5170ab7c291af2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20760-6https://doaj.org/toc/2041-1723Skeletal muscle has a remarkable regenerative capacity, which can largely be attributed to resident muscle stem cells (MuSCs). Here, the authors review the molecular mechanisms regulating MuSC quiescence, activation and proliferation, how these processes are regulated by the stem cell niche, and the role of MuSCs in neuromuscular diseases.F. RelaixM. BenczeM. J. BorokA. Der VartanianF. GattazzoD. MademtzoglouS. Perez-DiazA. ProlaP. C. Reyes-FernandezA. RotiniTagliettiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q F. Relaix M. Bencze M. J. Borok A. Der Vartanian F. Gattazzo D. Mademtzoglou S. Perez-Diaz A. Prola P. C. Reyes-Fernandez A. Rotini Taglietti Perspectives on skeletal muscle stem cells
description	Skeletal muscle has a remarkable regenerative capacity, which can largely be attributed to resident muscle stem cells (MuSCs). Here, the authors review the molecular mechanisms regulating MuSC quiescence, activation and proliferation, how these processes are regulated by the stem cell niche, and the role of MuSCs in neuromuscular diseases.
format	article
author	F. Relaix M. Bencze M. J. Borok A. Der Vartanian F. Gattazzo D. Mademtzoglou S. Perez-Diaz A. Prola P. C. Reyes-Fernandez A. Rotini Taglietti
author_facet	F. Relaix M. Bencze M. J. Borok A. Der Vartanian F. Gattazzo D. Mademtzoglou S. Perez-Diaz A. Prola P. C. Reyes-Fernandez A. Rotini Taglietti
author_sort	F. Relaix
title	Perspectives on skeletal muscle stem cells
title_short	Perspectives on skeletal muscle stem cells
title_full	Perspectives on skeletal muscle stem cells
title_fullStr	Perspectives on skeletal muscle stem cells
title_full_unstemmed	Perspectives on skeletal muscle stem cells
title_sort	perspectives on skeletal muscle stem cells
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/458d5c3a713043e5bfa5170ab7c291af
work_keys_str_mv	AT frelaix perspectivesonskeletalmusclestemcells AT mbencze perspectivesonskeletalmusclestemcells AT mjborok perspectivesonskeletalmusclestemcells AT adervartanian perspectivesonskeletalmusclestemcells AT fgattazzo perspectivesonskeletalmusclestemcells AT dmademtzoglou perspectivesonskeletalmusclestemcells AT sperezdiaz perspectivesonskeletalmusclestemcells AT aprola perspectivesonskeletalmusclestemcells AT pcreyesfernandez perspectivesonskeletalmusclestemcells AT arotini perspectivesonskeletalmusclestemcells AT taglietti perspectivesonskeletalmusclestemcells
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Perspectives on skeletal muscle stem cells

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