Inter-Ocular Symmetry of Vascular Density and Retinal Thickness in Unilateral Anisometropic Amblyopia

Zerrin Bayraktar, Seren Pehlivanoglu, Sukru Bayraktar, Sinan Albayrak, Muharrem Karakaya Department of Ophthalmology, Ozel Gaziosmanpasa Hospital, Yeni Yuzyil University School of Medicine, Istanbul, TurkeyCorrespondence: Zerrin Bayraktar Sahrayicedit Mah, Cami Sok, No. 30 Emintas Camlik Sitesi A, B...

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Autores principales:	Bayraktar Z, Pehlivanoglu S, Bayraktar S, Albayrak S, Karakaya M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	anisometropic amblyopia hyperopia optical coherence tomography angiography inter-ocular symmetry Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/45a0aae15b0a46bf915482f29ab25925
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spelling	oai:doaj.org-article:45a0aae15b0a46bf915482f29ab259252021-12-02T06:51:27ZInter-Ocular Symmetry of Vascular Density and Retinal Thickness in Unilateral Anisometropic Amblyopia1177-5483https://doaj.org/article/45a0aae15b0a46bf915482f29ab259252020-05-01T00:00:00Zhttps://www.dovepress.com/inter-ocular-symmetry-of-vascular-density-and-retinal-thickness-in-uni-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Zerrin Bayraktar, Seren Pehlivanoglu, Sukru Bayraktar, Sinan Albayrak, Muharrem Karakaya Department of Ophthalmology, Ozel Gaziosmanpasa Hospital, Yeni Yuzyil University School of Medicine, Istanbul, TurkeyCorrespondence: Zerrin Bayraktar Sahrayicedit Mah, Cami Sok, No. 30 Emintas Camlik Sitesi A, Blok D 10, Kadıkoy, Istanbul 34734, TurkeyTel +90 5337618977Email zerrinbayraktar@yahoo.comBackground: Inter-ocular symmetry of macular vascular anatomy in healthy subjects has been well documented in previous optical coherence tomography angiography (OCTA) studies. In our present study, we have demonstrated that the presence of anisometropic amblyopia in one eye does not alter this unique feature significantly. We investigated whether the presence of unilateral anisometropic amblyopia due to moderate amounts of hyperopia and/or astigmatism would have any significant influence on measurements of retinal thickness (RT) and superficial vessel density (SVD) in adult subjects.Subjects and methods: In the study group, both eyes of 21 adult subjects with unilateral anisometropic amblyopia were enrolled. Only one eye of an age-matched control group including 33 subjects was randomly selected. RT and SVD were measured in foveal and parafoveal retinal areas and compared in amblyopic eyes, their fellow eyes and in the control group. Inter-ocular symmetry of RT and SVD in amblyopic and fellow eyes were investigated by using correlation analysis.Results: There were statistically significant inter-ocular correlations of foveal and parafoveal RT in amblyopic and fellow eyes (P < 0.0001, for both). Foveal and parafoveal RT of the control group were not statistically different from amblyopic eyes (P = 0.072 and P = 0.46, respectively). There was no difference between foveal SVD of amblyopic eyes and control group (P = 0.10) and a significant inter-ocular correlation was found between amblyopic and fellow eyes (P = 0.029).Conclusion: For our adult subjects, none of the investigated OCTA parameters of the amblyopic eyes were found to be statistically different from those of age-matched controls. The preservation of inter-ocular symmetry in the amblyopic and fellow eyes implies that the influence of anisometropic amblyopia in one eye would be relatively small and negligible on routine OCTA examination.Keywords: anisometropic amblyopia, hyperopia, optical coherence tomography angiography, inter-ocular symmetryBayraktar ZPehlivanoglu SBayraktar SAlbayrak SKarakaya MDove Medical Pressarticleanisometropic amblyopiahyperopiaoptical coherence tomography angiographyinter-ocular symmetryOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 1261-1267 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	anisometropic amblyopia hyperopia optical coherence tomography angiography inter-ocular symmetry Ophthalmology RE1-994
spellingShingle	anisometropic amblyopia hyperopia optical coherence tomography angiography inter-ocular symmetry Ophthalmology RE1-994 Bayraktar Z Pehlivanoglu S Bayraktar S Albayrak S Karakaya M Inter-Ocular Symmetry of Vascular Density and Retinal Thickness in Unilateral Anisometropic Amblyopia
description	Zerrin Bayraktar, Seren Pehlivanoglu, Sukru Bayraktar, Sinan Albayrak, Muharrem Karakaya Department of Ophthalmology, Ozel Gaziosmanpasa Hospital, Yeni Yuzyil University School of Medicine, Istanbul, TurkeyCorrespondence: Zerrin Bayraktar Sahrayicedit Mah, Cami Sok, No. 30 Emintas Camlik Sitesi A, Blok D 10, Kadıkoy, Istanbul 34734, TurkeyTel +90 5337618977Email zerrinbayraktar@yahoo.comBackground: Inter-ocular symmetry of macular vascular anatomy in healthy subjects has been well documented in previous optical coherence tomography angiography (OCTA) studies. In our present study, we have demonstrated that the presence of anisometropic amblyopia in one eye does not alter this unique feature significantly. We investigated whether the presence of unilateral anisometropic amblyopia due to moderate amounts of hyperopia and/or astigmatism would have any significant influence on measurements of retinal thickness (RT) and superficial vessel density (SVD) in adult subjects.Subjects and methods: In the study group, both eyes of 21 adult subjects with unilateral anisometropic amblyopia were enrolled. Only one eye of an age-matched control group including 33 subjects was randomly selected. RT and SVD were measured in foveal and parafoveal retinal areas and compared in amblyopic eyes, their fellow eyes and in the control group. Inter-ocular symmetry of RT and SVD in amblyopic and fellow eyes were investigated by using correlation analysis.Results: There were statistically significant inter-ocular correlations of foveal and parafoveal RT in amblyopic and fellow eyes (P < 0.0001, for both). Foveal and parafoveal RT of the control group were not statistically different from amblyopic eyes (P = 0.072 and P = 0.46, respectively). There was no difference between foveal SVD of amblyopic eyes and control group (P = 0.10) and a significant inter-ocular correlation was found between amblyopic and fellow eyes (P = 0.029).Conclusion: For our adult subjects, none of the investigated OCTA parameters of the amblyopic eyes were found to be statistically different from those of age-matched controls. The preservation of inter-ocular symmetry in the amblyopic and fellow eyes implies that the influence of anisometropic amblyopia in one eye would be relatively small and negligible on routine OCTA examination.Keywords: anisometropic amblyopia, hyperopia, optical coherence tomography angiography, inter-ocular symmetry
format	article
author	Bayraktar Z Pehlivanoglu S Bayraktar S Albayrak S Karakaya M
author_facet	Bayraktar Z Pehlivanoglu S Bayraktar S Albayrak S Karakaya M
author_sort	Bayraktar Z
title	Inter-Ocular Symmetry of Vascular Density and Retinal Thickness in Unilateral Anisometropic Amblyopia
title_short	Inter-Ocular Symmetry of Vascular Density and Retinal Thickness in Unilateral Anisometropic Amblyopia
title_full	Inter-Ocular Symmetry of Vascular Density and Retinal Thickness in Unilateral Anisometropic Amblyopia
title_fullStr	Inter-Ocular Symmetry of Vascular Density and Retinal Thickness in Unilateral Anisometropic Amblyopia
title_full_unstemmed	Inter-Ocular Symmetry of Vascular Density and Retinal Thickness in Unilateral Anisometropic Amblyopia
title_sort	inter-ocular symmetry of vascular density and retinal thickness in unilateral anisometropic amblyopia
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/45a0aae15b0a46bf915482f29ab25925
work_keys_str_mv	AT bayraktarz interocularsymmetryofvasculardensityandretinalthicknessinunilateralanisometropicamblyopia AT pehlivanoglus interocularsymmetryofvasculardensityandretinalthicknessinunilateralanisometropicamblyopia AT bayraktars interocularsymmetryofvasculardensityandretinalthicknessinunilateralanisometropicamblyopia AT albayraks interocularsymmetryofvasculardensityandretinalthicknessinunilateralanisometropicamblyopia AT karakayam interocularsymmetryofvasculardensityandretinalthicknessinunilateralanisometropicamblyopia
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Inter-Ocular Symmetry of Vascular Density and Retinal Thickness in Unilateral Anisometropic Amblyopia

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