Network analysis reveals rare disease signatures across multiple levels of biological organization
Despite the clear causal relationship between genotype and phenotype in rare diseases, identifying the pathobiological mechanisms at various levels of biological organization remains a practical and conceptual challenge. Here, the authors introduce a network approach for evaluating the impact of rar...
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Main Authors: | Pisanu Buphamalai, Tomislav Kokotovic, Vanja Nagy, Jörg Menche |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/45ac36fef3284a0c8a60f92f22f0bb0f |
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