Network analysis reveals rare disease signatures across multiple levels of biological organization

Despite the clear causal relationship between genotype and phenotype in rare diseases, identifying the pathobiological mechanisms at various levels of biological organization remains a practical and conceptual challenge. Here, the authors introduce a network approach for evaluating the impact of rar...

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Auteurs principaux: Pisanu Buphamalai, Tomislav Kokotovic, Vanja Nagy, Jörg Menche
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/45ac36fef3284a0c8a60f92f22f0bb0f
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