Evolutionary history of teleost intron-containing and intron-less rhodopsin genes

Abstract Recent progress in whole genome sequencing has revealed that animals have various kinds of opsin genes for photoreception. Among them, most opsin genes have introns in their coding regions. However, it has been known for a long time that teleost retinas express intron-less rhodopsin genes,...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Chihiro Fujiyabu, Keita Sato, Ni Made Laksmi Utari, Hideyo Ohuchi, Yoshinori Shichida, Takahiro Yamashita
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/45b0cd8d0a9c46d8adf51fcc7e71fe64
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:45b0cd8d0a9c46d8adf51fcc7e71fe64
record_format	dspace
spelling	oai:doaj.org-article:45b0cd8d0a9c46d8adf51fcc7e71fe642021-12-02T15:09:40ZEvolutionary history of teleost intron-containing and intron-less rhodopsin genes10.1038/s41598-019-47028-42045-2322https://doaj.org/article/45b0cd8d0a9c46d8adf51fcc7e71fe642019-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-019-47028-4https://doaj.org/toc/2045-2322Abstract Recent progress in whole genome sequencing has revealed that animals have various kinds of opsin genes for photoreception. Among them, most opsin genes have introns in their coding regions. However, it has been known for a long time that teleost retinas express intron-less rhodopsin genes, which are presumed to have been formed by retroduplication from an ancestral intron-containing rhodopsin gene. In addition, teleosts have an intron-containing rhodopsin gene (exo-rhodopsin) exclusively for pineal photoreception. In this study, to unravel the evolutionary origin of the two teleost rhodopsin genes, we analyzed the rhodopsin genes of non-teleost fishes in the Actinopterygii. The phylogenetic analysis of full-length sequences of bichir, sturgeon and gar rhodopsins revealed that retroduplication of the rhodopsin gene occurred after branching of the bichir lineage. In addition, analysis of the tissue distribution and the molecular properties of bichir, sturgeon and gar rhodopsins showed that the abundant and exclusive expression of intron-containing rhodopsin in the pineal gland and the short lifetime of its meta II intermediate, which leads to optimization for pineal photoreception, were achieved after branching of the gar lineage. Based on these results, we propose a stepwise evolutionary model of teleost intron-containing and intron-less rhodopsin genes.Chihiro FujiyabuKeita SatoNi Made Laksmi UtariHideyo OhuchiYoshinori ShichidaTakahiro YamashitaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Chihiro Fujiyabu Keita Sato Ni Made Laksmi Utari Hideyo Ohuchi Yoshinori Shichida Takahiro Yamashita Evolutionary history of teleost intron-containing and intron-less rhodopsin genes
description	Abstract Recent progress in whole genome sequencing has revealed that animals have various kinds of opsin genes for photoreception. Among them, most opsin genes have introns in their coding regions. However, it has been known for a long time that teleost retinas express intron-less rhodopsin genes, which are presumed to have been formed by retroduplication from an ancestral intron-containing rhodopsin gene. In addition, teleosts have an intron-containing rhodopsin gene (exo-rhodopsin) exclusively for pineal photoreception. In this study, to unravel the evolutionary origin of the two teleost rhodopsin genes, we analyzed the rhodopsin genes of non-teleost fishes in the Actinopterygii. The phylogenetic analysis of full-length sequences of bichir, sturgeon and gar rhodopsins revealed that retroduplication of the rhodopsin gene occurred after branching of the bichir lineage. In addition, analysis of the tissue distribution and the molecular properties of bichir, sturgeon and gar rhodopsins showed that the abundant and exclusive expression of intron-containing rhodopsin in the pineal gland and the short lifetime of its meta II intermediate, which leads to optimization for pineal photoreception, were achieved after branching of the gar lineage. Based on these results, we propose a stepwise evolutionary model of teleost intron-containing and intron-less rhodopsin genes.
format	article
author	Chihiro Fujiyabu Keita Sato Ni Made Laksmi Utari Hideyo Ohuchi Yoshinori Shichida Takahiro Yamashita
author_facet	Chihiro Fujiyabu Keita Sato Ni Made Laksmi Utari Hideyo Ohuchi Yoshinori Shichida Takahiro Yamashita
author_sort	Chihiro Fujiyabu
title	Evolutionary history of teleost intron-containing and intron-less rhodopsin genes
title_short	Evolutionary history of teleost intron-containing and intron-less rhodopsin genes
title_full	Evolutionary history of teleost intron-containing and intron-less rhodopsin genes
title_fullStr	Evolutionary history of teleost intron-containing and intron-less rhodopsin genes
title_full_unstemmed	Evolutionary history of teleost intron-containing and intron-less rhodopsin genes
title_sort	evolutionary history of teleost intron-containing and intron-less rhodopsin genes
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/45b0cd8d0a9c46d8adf51fcc7e71fe64
work_keys_str_mv	AT chihirofujiyabu evolutionaryhistoryofteleostintroncontainingandintronlessrhodopsingenes AT keitasato evolutionaryhistoryofteleostintroncontainingandintronlessrhodopsingenes AT nimadelaksmiutari evolutionaryhistoryofteleostintroncontainingandintronlessrhodopsingenes AT hideyoohuchi evolutionaryhistoryofteleostintroncontainingandintronlessrhodopsingenes AT yoshinorishichida evolutionaryhistoryofteleostintroncontainingandintronlessrhodopsingenes AT takahiroyamashita evolutionaryhistoryofteleostintroncontainingandintronlessrhodopsingenes
_version_	1718387748434345984

Evolutionary history of teleost intron-containing and intron-less rhodopsin genes

Ejemplares similares