DNA-enabled rational design of fluorescence-Raman bimodal nanoprobes for cancer imaging and therapy

Currently available Raman scanners are limited in speed to acquire images of clinically relevant sizes in cancer imaging. Here, the authors developed a DNA based design principle for Raman-Fluorescence bimodal nanoparticles and demonstrate real-time, high precision image-guided tumor resections and...

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Autores principales: Suchetan Pal, Angana Ray, Chrysafis Andreou, Yadong Zhou, Tatini Rakshit, Marek Wlodarczyk, Masatomo Maeda, Ricardo Toledo-Crow, Naxhije Berisha, Jiang Yang, Hsiao-Ting Hsu, Anton Oseledchyk, Jagannath Mondal, Shengli Zou, Moritz F. Kircher
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/45b115ea90ac4c3fb323dba659f6adf6
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Sumario:Currently available Raman scanners are limited in speed to acquire images of clinically relevant sizes in cancer imaging. Here, the authors developed a DNA based design principle for Raman-Fluorescence bimodal nanoparticles and demonstrate real-time, high precision image-guided tumor resections and photothermal ablation of cancer.