DNA-enabled rational design of fluorescence-Raman bimodal nanoprobes for cancer imaging and therapy

Currently available Raman scanners are limited in speed to acquire images of clinically relevant sizes in cancer imaging. Here, the authors developed a DNA based design principle for Raman-Fluorescence bimodal nanoparticles and demonstrate real-time, high precision image-guided tumor resections and...

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Autores principales: Suchetan Pal, Angana Ray, Chrysafis Andreou, Yadong Zhou, Tatini Rakshit, Marek Wlodarczyk, Masatomo Maeda, Ricardo Toledo-Crow, Naxhije Berisha, Jiang Yang, Hsiao-Ting Hsu, Anton Oseledchyk, Jagannath Mondal, Shengli Zou, Moritz F. Kircher
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/45b115ea90ac4c3fb323dba659f6adf6
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spelling oai:doaj.org-article:45b115ea90ac4c3fb323dba659f6adf62021-12-02T16:57:35ZDNA-enabled rational design of fluorescence-Raman bimodal nanoprobes for cancer imaging and therapy10.1038/s41467-019-09173-22041-1723https://doaj.org/article/45b115ea90ac4c3fb323dba659f6adf62019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09173-2https://doaj.org/toc/2041-1723Currently available Raman scanners are limited in speed to acquire images of clinically relevant sizes in cancer imaging. Here, the authors developed a DNA based design principle for Raman-Fluorescence bimodal nanoparticles and demonstrate real-time, high precision image-guided tumor resections and photothermal ablation of cancer.Suchetan PalAngana RayChrysafis AndreouYadong ZhouTatini RakshitMarek WlodarczykMasatomo MaedaRicardo Toledo-CrowNaxhije BerishaJiang YangHsiao-Ting HsuAnton OseledchykJagannath MondalShengli ZouMoritz F. KircherNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Suchetan Pal
Angana Ray
Chrysafis Andreou
Yadong Zhou
Tatini Rakshit
Marek Wlodarczyk
Masatomo Maeda
Ricardo Toledo-Crow
Naxhije Berisha
Jiang Yang
Hsiao-Ting Hsu
Anton Oseledchyk
Jagannath Mondal
Shengli Zou
Moritz F. Kircher
DNA-enabled rational design of fluorescence-Raman bimodal nanoprobes for cancer imaging and therapy
description Currently available Raman scanners are limited in speed to acquire images of clinically relevant sizes in cancer imaging. Here, the authors developed a DNA based design principle for Raman-Fluorescence bimodal nanoparticles and demonstrate real-time, high precision image-guided tumor resections and photothermal ablation of cancer.
format article
author Suchetan Pal
Angana Ray
Chrysafis Andreou
Yadong Zhou
Tatini Rakshit
Marek Wlodarczyk
Masatomo Maeda
Ricardo Toledo-Crow
Naxhije Berisha
Jiang Yang
Hsiao-Ting Hsu
Anton Oseledchyk
Jagannath Mondal
Shengli Zou
Moritz F. Kircher
author_facet Suchetan Pal
Angana Ray
Chrysafis Andreou
Yadong Zhou
Tatini Rakshit
Marek Wlodarczyk
Masatomo Maeda
Ricardo Toledo-Crow
Naxhije Berisha
Jiang Yang
Hsiao-Ting Hsu
Anton Oseledchyk
Jagannath Mondal
Shengli Zou
Moritz F. Kircher
author_sort Suchetan Pal
title DNA-enabled rational design of fluorescence-Raman bimodal nanoprobes for cancer imaging and therapy
title_short DNA-enabled rational design of fluorescence-Raman bimodal nanoprobes for cancer imaging and therapy
title_full DNA-enabled rational design of fluorescence-Raman bimodal nanoprobes for cancer imaging and therapy
title_fullStr DNA-enabled rational design of fluorescence-Raman bimodal nanoprobes for cancer imaging and therapy
title_full_unstemmed DNA-enabled rational design of fluorescence-Raman bimodal nanoprobes for cancer imaging and therapy
title_sort dna-enabled rational design of fluorescence-raman bimodal nanoprobes for cancer imaging and therapy
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/45b115ea90ac4c3fb323dba659f6adf6
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