Current and Emerging DMARDs for the Treatment of Rheumatoid Arthritis

Eduardo Mysler, Mariana Caubet, Ana Lizarraga Organización Medica de Investigación, Buenos Aires, ArgentinaCorrespondence: Eduardo Mysler Email e.mysler@omiargentina.com.arAbstract: Rheumatoid arthritis (RA) is the most prevalent form of inflammatory arthritis. It is a profound...

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Autores principales: Mysler E, Caubet M, Lizarraga A
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Publicado: Dove Medical Press 2021
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spelling oai:doaj.org-article:45b1d4dc816145d7b84c99f4c59ddaae2021-12-02T14:38:25ZCurrent and Emerging DMARDs for the Treatment of Rheumatoid Arthritis1179-156Xhttps://doaj.org/article/45b1d4dc816145d7b84c99f4c59ddaae2021-06-01T00:00:00Zhttps://www.dovepress.com/current-and-emerging-dmards-for-the-treatment-of-rheumatoid-arthritis-peer-reviewed-fulltext-article-OARRRhttps://doaj.org/toc/1179-156XEduardo Mysler, Mariana Caubet, Ana Lizarraga Organización Medica de Investigación, Buenos Aires, ArgentinaCorrespondence: Eduardo Mysler Email e.mysler@omiargentina.com.arAbstract: Rheumatoid arthritis (RA) is the most prevalent form of inflammatory arthritis. It is a profoundly serious and severe disease that if it goes untreated could have severe consequences to the joints and health of the patient who carries this diagnosis. The treatment of RA has dramatically changed since the year 2000, with the discovery of the TNFis, then other biologics, and finally the JAKi. All these new medications with or without methotrexate in combination, tight control and treat to target have produced a revolution in the outcome of this disease. We reviewed and summarized the treatment options, and the most significant papers for each one of these new drugs. The reader could have a full picture with all the references of the recent publications. We also updated the biosimilar situation in RA, as well as the new drugs that will be coming to the market in the next 5 years.Keywords: rheumatoid arthritis, DMARDs, biosimilarsMysler ECaubet MLizarraga ADove Medical Pressarticlerheumatoid arthritisdmardsbiosimilars.Diseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol Volume 13, Pp 139-152 (2021)
institution DOAJ
collection DOAJ
language EN
topic rheumatoid arthritis
dmards
biosimilars.
Diseases of the musculoskeletal system
RC925-935
spellingShingle rheumatoid arthritis
dmards
biosimilars.
Diseases of the musculoskeletal system
RC925-935
Mysler E
Caubet M
Lizarraga A
Current and Emerging DMARDs for the Treatment of Rheumatoid Arthritis
description Eduardo Mysler, Mariana Caubet, Ana Lizarraga Organización Medica de Investigación, Buenos Aires, ArgentinaCorrespondence: Eduardo Mysler Email e.mysler@omiargentina.com.arAbstract: Rheumatoid arthritis (RA) is the most prevalent form of inflammatory arthritis. It is a profoundly serious and severe disease that if it goes untreated could have severe consequences to the joints and health of the patient who carries this diagnosis. The treatment of RA has dramatically changed since the year 2000, with the discovery of the TNFis, then other biologics, and finally the JAKi. All these new medications with or without methotrexate in combination, tight control and treat to target have produced a revolution in the outcome of this disease. We reviewed and summarized the treatment options, and the most significant papers for each one of these new drugs. The reader could have a full picture with all the references of the recent publications. We also updated the biosimilar situation in RA, as well as the new drugs that will be coming to the market in the next 5 years.Keywords: rheumatoid arthritis, DMARDs, biosimilars
format article
author Mysler E
Caubet M
Lizarraga A
author_facet Mysler E
Caubet M
Lizarraga A
author_sort Mysler E
title Current and Emerging DMARDs for the Treatment of Rheumatoid Arthritis
title_short Current and Emerging DMARDs for the Treatment of Rheumatoid Arthritis
title_full Current and Emerging DMARDs for the Treatment of Rheumatoid Arthritis
title_fullStr Current and Emerging DMARDs for the Treatment of Rheumatoid Arthritis
title_full_unstemmed Current and Emerging DMARDs for the Treatment of Rheumatoid Arthritis
title_sort current and emerging dmards for the treatment of rheumatoid arthritis
publisher Dove Medical Press
publishDate 2021
url https://doaj.org/article/45b1d4dc816145d7b84c99f4c59ddaae
work_keys_str_mv AT myslere currentandemergingdmardsforthetreatmentofrheumatoidarthritis
AT caubetm currentandemergingdmardsforthetreatmentofrheumatoidarthritis
AT lizarragaa currentandemergingdmardsforthetreatmentofrheumatoidarthritis
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