Global mapping of protein–metabolite interactions in Saccharomyces cerevisiae reveals that Ser-Leu dipeptide regulates phosphoglycerate kinase activity

Global mapping of protein–metabolite interactions in Saccharomyces cerevisiae reveals that Ser-Leu dipeptide regulates phosphoglycerate kinase activity

Marcin Luzarowski et al. use a new method PROMIS for systematic analysis of protein small molecule interactions in yeast. Their work provides an experimentally-derived catalogue of protein–metabolite complexes in S. cerevisiae and reveals that the Ser-Leu dipeptide activates Pgk1, and alters cellula...

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Autores principales: Marcin Luzarowski, Rubén Vicente, Andrei Kiselev, Mateusz Wagner, Dennis Schlossarek, Alexander Erban, Leonardo Perez de Souza, Dorothee Childs, Izabela Wojciechowska, Urszula Luzarowska, Michał Górka, Ewelina M. Sokołowska, Monika Kosmacz, Juan C. Moreno, Aleksandra Brzezińska, Bhavana Vegesna, Joachim Kopka, Alisdair R. Fernie, Lothar Willmitzer, Jennifer C. Ewald, Aleksandra Skirycz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/45b3e29eed33443991958a1e995a67de
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spelling oai:doaj.org-article:45b3e29eed33443991958a1e995a67de2021-12-02T14:26:46ZGlobal mapping of protein–metabolite interactions in Saccharomyces cerevisiae reveals that Ser-Leu dipeptide regulates phosphoglycerate kinase activity10.1038/s42003-021-01684-32399-3642https://doaj.org/article/45b3e29eed33443991958a1e995a67de2021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01684-3https://doaj.org/toc/2399-3642Marcin Luzarowski et al. use a new method PROMIS for systematic analysis of protein small molecule interactions in yeast. Their work provides an experimentally-derived catalogue of protein–metabolite complexes in S. cerevisiae and reveals that the Ser-Leu dipeptide activates Pgk1, and alters cellular metabolism.Marcin LuzarowskiRubén VicenteAndrei KiselevMateusz WagnerDennis SchlossarekAlexander ErbanLeonardo Perez de SouzaDorothee ChildsIzabela WojciechowskaUrszula LuzarowskaMichał GórkaEwelina M. SokołowskaMonika KosmaczJuan C. MorenoAleksandra BrzezińskaBhavana VegesnaJoachim KopkaAlisdair R. FernieLothar WillmitzerJennifer C. EwaldAleksandra SkiryczNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Marcin Luzarowski
Rubén Vicente
Andrei Kiselev
Mateusz Wagner
Dennis Schlossarek
Alexander Erban
Leonardo Perez de Souza
Dorothee Childs
Izabela Wojciechowska
Urszula Luzarowska
Michał Górka
Ewelina M. Sokołowska
Monika Kosmacz
Juan C. Moreno
Aleksandra Brzezińska
Bhavana Vegesna
Joachim Kopka
Alisdair R. Fernie
Lothar Willmitzer
Jennifer C. Ewald
Aleksandra Skirycz
Global mapping of protein–metabolite interactions in Saccharomyces cerevisiae reveals that Ser-Leu dipeptide regulates phosphoglycerate kinase activity
description Marcin Luzarowski et al. use a new method PROMIS for systematic analysis of protein small molecule interactions in yeast. Their work provides an experimentally-derived catalogue of protein–metabolite complexes in S. cerevisiae and reveals that the Ser-Leu dipeptide activates Pgk1, and alters cellular metabolism.
format article
author Marcin Luzarowski
Rubén Vicente
Andrei Kiselev
Mateusz Wagner
Dennis Schlossarek
Alexander Erban
Leonardo Perez de Souza
Dorothee Childs
Izabela Wojciechowska
Urszula Luzarowska
Michał Górka
Ewelina M. Sokołowska
Monika Kosmacz
Juan C. Moreno
Aleksandra Brzezińska
Bhavana Vegesna
Joachim Kopka
Alisdair R. Fernie
Lothar Willmitzer
Jennifer C. Ewald
Aleksandra Skirycz
author_facet Marcin Luzarowski
Rubén Vicente
Andrei Kiselev
Mateusz Wagner
Dennis Schlossarek
Alexander Erban
Leonardo Perez de Souza
Dorothee Childs
Izabela Wojciechowska
Urszula Luzarowska
Michał Górka
Ewelina M. Sokołowska
Monika Kosmacz
Juan C. Moreno
Aleksandra Brzezińska
Bhavana Vegesna
Joachim Kopka
Alisdair R. Fernie
Lothar Willmitzer
Jennifer C. Ewald
Aleksandra Skirycz
author_sort Marcin Luzarowski
title Global mapping of protein–metabolite interactions in Saccharomyces cerevisiae reveals that Ser-Leu dipeptide regulates phosphoglycerate kinase activity
title_short Global mapping of protein–metabolite interactions in Saccharomyces cerevisiae reveals that Ser-Leu dipeptide regulates phosphoglycerate kinase activity
title_full Global mapping of protein–metabolite interactions in Saccharomyces cerevisiae reveals that Ser-Leu dipeptide regulates phosphoglycerate kinase activity
title_fullStr Global mapping of protein–metabolite interactions in Saccharomyces cerevisiae reveals that Ser-Leu dipeptide regulates phosphoglycerate kinase activity
title_full_unstemmed Global mapping of protein–metabolite interactions in Saccharomyces cerevisiae reveals that Ser-Leu dipeptide regulates phosphoglycerate kinase activity
title_sort global mapping of protein–metabolite interactions in saccharomyces cerevisiae reveals that ser-leu dipeptide regulates phosphoglycerate kinase activity
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/45b3e29eed33443991958a1e995a67de
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