Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion

Organs from donors with transmissible viral infections, such as hepatitis C virus (HCV), are not offered for transplantation due to a high risk of transmission. Here, Galasso et al. develop a method for treatment of HCV-infected human donor lungs that is safe and prevents HCV transmission in the pig...

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Autores principales: Marcos Galasso, Jordan J. Feld, Yui Watanabe, Mauricio Pipkin, Cara Summers, Aadil Ali, Robert Qaqish, Manyin Chen, Rafaela V. P. Ribeiro, Khaled Ramadan, Layla Pires, Vanderlei S. Bagnato, Cristina Kurachi, Vera Cherepanov, Gray Moonen, Anajara Gazzalle, Thomas K. Waddell, Mingyao Liu, Shaf Keshavjee, Brian C. Wilson, Atul Humar, Marcelo Cypel
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Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/45c1acfb0bbf4b10a32fc0a6f9ffc4f0
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spelling oai:doaj.org-article:45c1acfb0bbf4b10a32fc0a6f9ffc4f02021-12-02T15:35:59ZInactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion10.1038/s41467-018-08261-z2041-1723https://doaj.org/article/45c1acfb0bbf4b10a32fc0a6f9ffc4f02019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08261-zhttps://doaj.org/toc/2041-1723Organs from donors with transmissible viral infections, such as hepatitis C virus (HCV), are not offered for transplantation due to a high risk of transmission. Here, Galasso et al. develop a method for treatment of HCV-infected human donor lungs that is safe and prevents HCV transmission in the pig model.Marcos GalassoJordan J. FeldYui WatanabeMauricio PipkinCara SummersAadil AliRobert QaqishManyin ChenRafaela V. P. RibeiroKhaled RamadanLayla PiresVanderlei S. BagnatoCristina KurachiVera CherepanovGray MoonenAnajara GazzalleThomas K. WaddellMingyao LiuShaf KeshavjeeBrian C. WilsonAtul HumarMarcelo CypelNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Marcos Galasso
Jordan J. Feld
Yui Watanabe
Mauricio Pipkin
Cara Summers
Aadil Ali
Robert Qaqish
Manyin Chen
Rafaela V. P. Ribeiro
Khaled Ramadan
Layla Pires
Vanderlei S. Bagnato
Cristina Kurachi
Vera Cherepanov
Gray Moonen
Anajara Gazzalle
Thomas K. Waddell
Mingyao Liu
Shaf Keshavjee
Brian C. Wilson
Atul Humar
Marcelo Cypel
Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion
description Organs from donors with transmissible viral infections, such as hepatitis C virus (HCV), are not offered for transplantation due to a high risk of transmission. Here, Galasso et al. develop a method for treatment of HCV-infected human donor lungs that is safe and prevents HCV transmission in the pig model.
format article
author Marcos Galasso
Jordan J. Feld
Yui Watanabe
Mauricio Pipkin
Cara Summers
Aadil Ali
Robert Qaqish
Manyin Chen
Rafaela V. P. Ribeiro
Khaled Ramadan
Layla Pires
Vanderlei S. Bagnato
Cristina Kurachi
Vera Cherepanov
Gray Moonen
Anajara Gazzalle
Thomas K. Waddell
Mingyao Liu
Shaf Keshavjee
Brian C. Wilson
Atul Humar
Marcelo Cypel
author_facet Marcos Galasso
Jordan J. Feld
Yui Watanabe
Mauricio Pipkin
Cara Summers
Aadil Ali
Robert Qaqish
Manyin Chen
Rafaela V. P. Ribeiro
Khaled Ramadan
Layla Pires
Vanderlei S. Bagnato
Cristina Kurachi
Vera Cherepanov
Gray Moonen
Anajara Gazzalle
Thomas K. Waddell
Mingyao Liu
Shaf Keshavjee
Brian C. Wilson
Atul Humar
Marcelo Cypel
author_sort Marcos Galasso
title Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion
title_short Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion
title_full Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion
title_fullStr Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion
title_full_unstemmed Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion
title_sort inactivating hepatitis c virus in donor lungs using light therapies during normothermic ex vivo lung perfusion
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/45c1acfb0bbf4b10a32fc0a6f9ffc4f0
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