A novel mechanism of soluble HLA-G mediated immune modulation: downregulation of T cell chemokine receptor expression and impairment of chemotaxis.

<h4>Background</h4>In recent years, many immunoregulatory functions have been ascribed to soluble HLA-G (sHLA-G). Since chemotaxis is crucial for an efficient immune response, we have investigated for the first time the effects of sHLA-G on chemokine receptor expression and function in d...

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Autores principales: Fabio Morandi, Elisa Ferretti, Paola Bocca, Ignazia Prigione, Lizzia Raffaghello, Vito Pistoia
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/45c76a94729640a99fddb6e4f1e26e2c
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