Prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study

Abstract We examined the association between maternal air purifier use during pregnancy and neurodevelopmental delay in toddlers by analysing data from 82,457 mother-toddler pairs. Air purifier use was measured using a simple yes/no question. Developmental delays at 1.5, 2.0, 2.5, and 3.0 years were...

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Autores principales:	Kenta Matsumura, Kei Hamazaki, Akiko Tsuchida, Hidekuni Inadera, The Japan Environment and Children’s Study (JECS) Group
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/45c9cd1adb844ffd908425d078576e31
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spelling	oai:doaj.org-article:45c9cd1adb844ffd908425d078576e312021-12-02T17:37:23ZProspective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study10.1038/s41598-021-98482-y2045-2322https://doaj.org/article/45c9cd1adb844ffd908425d078576e312021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-98482-yhttps://doaj.org/toc/2045-2322Abstract We examined the association between maternal air purifier use during pregnancy and neurodevelopmental delay in toddlers by analysing data from 82,457 mother-toddler pairs. Air purifier use was measured using a simple yes/no question. Developmental delays at 1.5, 2.0, 2.5, and 3.0 years were assessed using the Ages and Stages Questionnaire, Third Edition. Generalized additive mixed model analysis with 21 covariates revealed that air purifier use was associated with lower prevalence of developmental delay in all five areas—communication, gross motor, fine motor, problem solving, and personal-social—at all four time points (adjusted risk ratios ranged from 0.827 to 0.927, and only one 95% confidence interval crossed the reference). These findings suggest a negative association between air purifier use during pregnancy and neurodevelopmental delay in toddlers. Trial registration: UMIN000030786 (15/01/2018).Kenta MatsumuraKei HamazakiAkiko TsuchidaHidekuni InaderaThe Japan Environment and Children’s Study (JECS) GroupNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kenta Matsumura Kei Hamazaki Akiko Tsuchida Hidekuni Inadera The Japan Environment and Children’s Study (JECS) Group Prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study
description	Abstract We examined the association between maternal air purifier use during pregnancy and neurodevelopmental delay in toddlers by analysing data from 82,457 mother-toddler pairs. Air purifier use was measured using a simple yes/no question. Developmental delays at 1.5, 2.0, 2.5, and 3.0 years were assessed using the Ages and Stages Questionnaire, Third Edition. Generalized additive mixed model analysis with 21 covariates revealed that air purifier use was associated with lower prevalence of developmental delay in all five areas—communication, gross motor, fine motor, problem solving, and personal-social—at all four time points (adjusted risk ratios ranged from 0.827 to 0.927, and only one 95% confidence interval crossed the reference). These findings suggest a negative association between air purifier use during pregnancy and neurodevelopmental delay in toddlers. Trial registration: UMIN000030786 (15/01/2018).
format	article
author	Kenta Matsumura Kei Hamazaki Akiko Tsuchida Hidekuni Inadera The Japan Environment and Children’s Study (JECS) Group
author_facet	Kenta Matsumura Kei Hamazaki Akiko Tsuchida Hidekuni Inadera The Japan Environment and Children’s Study (JECS) Group
author_sort	Kenta Matsumura
title	Prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study
title_short	Prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study
title_full	Prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study
title_fullStr	Prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study
title_full_unstemmed	Prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study
title_sort	prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the japan environment and children’s study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/45c9cd1adb844ffd908425d078576e31
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Prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study

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