Study on magnetic thermal seeds coated with thermal-responsive molecularly imprinted polymers

We conceived a novel hybrid carrier of a thermal-responsive molecularly imprinted polymer (MIP) and a magnetic thermal seed (MTS) that showed a heat-generating ability under an alternate current (AC) magnetic field. Compared to our previous publications, we modify both the MIP and MTS to improve the...

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Autores principales:	Takuya Kubo, Miwa Shimonaka, Yoshiyuki Watabe, Kazunari Akiyoshi, Jeyadevan Balachandran, Koji Otsuka
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2021
Materias:	molecularly imprinted polymer magnetic thermal seed uniformly sized particles thermal-responsive hybridization drug release Materials of engineering and construction. Mechanics of materials TA401-492 Polymers and polymer manufacture TP1080-1185
Acceso en línea:	https://doaj.org/article/45cf041723014f899d4abb62fb799ebe
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spelling	oai:doaj.org-article:45cf041723014f899d4abb62fb799ebe2021-11-26T11:19:49ZStudy on magnetic thermal seeds coated with thermal-responsive molecularly imprinted polymers2055-03242055-033210.1080/20550324.2021.2008206https://doaj.org/article/45cf041723014f899d4abb62fb799ebe2021-11-01T00:00:00Zhttp://dx.doi.org/10.1080/20550324.2021.2008206https://doaj.org/toc/2055-0324https://doaj.org/toc/2055-0332We conceived a novel hybrid carrier of a thermal-responsive molecularly imprinted polymer (MIP) and a magnetic thermal seed (MTS) that showed a heat-generating ability under an alternate current (AC) magnetic field. Compared to our previous publications, we modify both the MIP and MTS to improve the feasibility for the hybrid carrier, briefly we have to achieve the accurate size control and narrower size distribution of MTS, and higher molecular recognition/release ability of MIP. Firstly, uniformly sized particles which are expected to show a large heat-generating ability under an AC magnetic field were successfully prepared by controlling the core creation. Then, an MIP targeted for selective adsorption of pemetrexed (PMX), a well-known anti-cancer drug, was prepared using N-carbobenzoxy-l-glutamic acid as a pseudo template. Finally, the preliminary hybridization of the MTS and the MIP-equivalent polymer coating was examined by introducing vinyl groups as methacrylic acid using a ligand exchanging method.Takuya KuboMiwa ShimonakaYoshiyuki WatabeKazunari AkiyoshiJeyadevan BalachandranKoji OtsukaTaylor & Francis Grouparticlemolecularly imprinted polymermagnetic thermal seeduniformly sized particlesthermal-responsivehybridizationdrug releaseMaterials of engineering and construction. Mechanics of materialsTA401-492Polymers and polymer manufactureTP1080-1185ENNanocomposites, Vol 0, Iss 0, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	molecularly imprinted polymer magnetic thermal seed uniformly sized particles thermal-responsive hybridization drug release Materials of engineering and construction. Mechanics of materials TA401-492 Polymers and polymer manufacture TP1080-1185
spellingShingle	molecularly imprinted polymer magnetic thermal seed uniformly sized particles thermal-responsive hybridization drug release Materials of engineering and construction. Mechanics of materials TA401-492 Polymers and polymer manufacture TP1080-1185 Takuya Kubo Miwa Shimonaka Yoshiyuki Watabe Kazunari Akiyoshi Jeyadevan Balachandran Koji Otsuka Study on magnetic thermal seeds coated with thermal-responsive molecularly imprinted polymers
description	We conceived a novel hybrid carrier of a thermal-responsive molecularly imprinted polymer (MIP) and a magnetic thermal seed (MTS) that showed a heat-generating ability under an alternate current (AC) magnetic field. Compared to our previous publications, we modify both the MIP and MTS to improve the feasibility for the hybrid carrier, briefly we have to achieve the accurate size control and narrower size distribution of MTS, and higher molecular recognition/release ability of MIP. Firstly, uniformly sized particles which are expected to show a large heat-generating ability under an AC magnetic field were successfully prepared by controlling the core creation. Then, an MIP targeted for selective adsorption of pemetrexed (PMX), a well-known anti-cancer drug, was prepared using N-carbobenzoxy-l-glutamic acid as a pseudo template. Finally, the preliminary hybridization of the MTS and the MIP-equivalent polymer coating was examined by introducing vinyl groups as methacrylic acid using a ligand exchanging method.
format	article
author	Takuya Kubo Miwa Shimonaka Yoshiyuki Watabe Kazunari Akiyoshi Jeyadevan Balachandran Koji Otsuka
author_facet	Takuya Kubo Miwa Shimonaka Yoshiyuki Watabe Kazunari Akiyoshi Jeyadevan Balachandran Koji Otsuka
author_sort	Takuya Kubo
title	Study on magnetic thermal seeds coated with thermal-responsive molecularly imprinted polymers
title_short	Study on magnetic thermal seeds coated with thermal-responsive molecularly imprinted polymers
title_full	Study on magnetic thermal seeds coated with thermal-responsive molecularly imprinted polymers
title_fullStr	Study on magnetic thermal seeds coated with thermal-responsive molecularly imprinted polymers
title_full_unstemmed	Study on magnetic thermal seeds coated with thermal-responsive molecularly imprinted polymers
title_sort	study on magnetic thermal seeds coated with thermal-responsive molecularly imprinted polymers
publisher	Taylor & Francis Group
publishDate	2021
url	https://doaj.org/article/45cf041723014f899d4abb62fb799ebe
work_keys_str_mv	AT takuyakubo studyonmagneticthermalseedscoatedwiththermalresponsivemolecularlyimprintedpolymers AT miwashimonaka studyonmagneticthermalseedscoatedwiththermalresponsivemolecularlyimprintedpolymers AT yoshiyukiwatabe studyonmagneticthermalseedscoatedwiththermalresponsivemolecularlyimprintedpolymers AT kazunariakiyoshi studyonmagneticthermalseedscoatedwiththermalresponsivemolecularlyimprintedpolymers AT jeyadevanbalachandran studyonmagneticthermalseedscoatedwiththermalresponsivemolecularlyimprintedpolymers AT kojiotsuka studyonmagneticthermalseedscoatedwiththermalresponsivemolecularlyimprintedpolymers
_version_	1718409465167872000

Study on magnetic thermal seeds coated with thermal-responsive molecularly imprinted polymers

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