Split-cre complementation indicates coincident activity of different genes in vivo.

Cre/LoxP recombination is the gold standard for conditional gene regulation in mice in vivo. However, promoters driving the expression of Cre recombinase are often active in a wide range of cell types and therefore unsuited to target more specific subsets of cells. To overcome this limitation, we de...

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Auteurs principaux: Johannes Hirrlinger, Anja Scheller, Petra G Hirrlinger, Beate Kellert, Wannan Tang, Michael C Wehr, Sandra Goebbels, Andreas Reichenbach, Rolf Sprengel, Moritz J Rossner, Frank Kirchhoff
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2009
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Accès en ligne:https://doaj.org/article/45cf49cd2e404783b72af995f3e94da0
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