Use of net reclassification improvement (NRI) method confirms the utility of combined genetic risk score to predict type 2 diabetes.

Use of net reclassification improvement (NRI) method confirms the utility of combined genetic risk score to predict type 2 diabetes.

<h4>Background</h4>Recent genome-wide association studies (GWAS) identified more than 70 novel loci for type 2 diabetes (T2D), some of which have been widely replicated in Asian populations. In this study, we investigated their individual and combined effects on T2D in a Chinese populati...

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Autores principales: Claudia H T Tam, Janice S K Ho, Ying Wang, Vincent K L Lam, Heung Man Lee, Guozhi Jiang, Eric S H Lau, Alice P S Kong, Xiaodan Fan, Jean L F Woo, Stephen K W Tsui, Maggie C Y Ng, Wing Yee So, Juliana C N Chan, Ronald C W Ma
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/45e049b9d1db45278d2b5c787b41bf48
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