Alterations in spontaneous brain oscillations during stroke recovery.

Amplitude or frequency alterations of spontaneous brain oscillations may reveal pathological phenomena in the brain or predict recovery from brain lesions, but the temporal evolution and the functional significance of these changes is not well known. We performed follow-up recordings of spontaneous...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kristina Laaksonen, Liisa Helle, Lauri Parkkonen, Erika Kirveskari, Jyrki P Mäkelä, Satu Mustanoja, Turgut Tatlisumak, Markku Kaste, Nina Forss
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/45e432b5ee9e4c48b786de78e6123835
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:45e432b5ee9e4c48b786de78e6123835
record_format	dspace
spelling	oai:doaj.org-article:45e432b5ee9e4c48b786de78e61238352021-11-18T07:49:44ZAlterations in spontaneous brain oscillations during stroke recovery.1932-620310.1371/journal.pone.0061146https://doaj.org/article/45e432b5ee9e4c48b786de78e61238352013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23593414/?tool=EBIhttps://doaj.org/toc/1932-6203Amplitude or frequency alterations of spontaneous brain oscillations may reveal pathological phenomena in the brain or predict recovery from brain lesions, but the temporal evolution and the functional significance of these changes is not well known. We performed follow-up recordings of spontaneous brain oscillations with whole-head MEG in 16 patients with first-ever stroke in the middle cerebral artery territory, affecting upper limb motor function, 1-7 days (T0), 1 month (T1), and 3 months (T2) after stroke, with concomitant clinical examination. Clinical test results improved significantly from T0 to T1 or T2. During recovery (at T1 and T2), the strength of temporo-parietal ≈ 10-Hz oscillations in the affected hemisphere (AH) was increased as compared with the unaffected hemisphere. Abnormal low-frequency magnetic activity (ALFMA) at ≈ 1 Hz in the AH was detected in the perilesional cortex in seven patients at T0. In four of these, ALFMA persisted at T2. In patients with ALFMA, the lesion size was significantly larger than in the rest of the patients, and worse clinical outcome was observed in patients with persisting ALFMA. Our results indicate that temporo-parietal ≈ 10-Hz oscillations are enhanced in the AH during recovery from stroke. Moreover, stroke causes ALFMA, which seems to persist in patients with worse clinical outcome.Kristina LaaksonenLiisa HelleLauri ParkkonenErika KirveskariJyrki P MäkeläSatu MustanojaTurgut TatlisumakMarkku KasteNina ForssPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 4, p e61146 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kristina Laaksonen Liisa Helle Lauri Parkkonen Erika Kirveskari Jyrki P Mäkelä Satu Mustanoja Turgut Tatlisumak Markku Kaste Nina Forss Alterations in spontaneous brain oscillations during stroke recovery.
description	Amplitude or frequency alterations of spontaneous brain oscillations may reveal pathological phenomena in the brain or predict recovery from brain lesions, but the temporal evolution and the functional significance of these changes is not well known. We performed follow-up recordings of spontaneous brain oscillations with whole-head MEG in 16 patients with first-ever stroke in the middle cerebral artery territory, affecting upper limb motor function, 1-7 days (T0), 1 month (T1), and 3 months (T2) after stroke, with concomitant clinical examination. Clinical test results improved significantly from T0 to T1 or T2. During recovery (at T1 and T2), the strength of temporo-parietal ≈ 10-Hz oscillations in the affected hemisphere (AH) was increased as compared with the unaffected hemisphere. Abnormal low-frequency magnetic activity (ALFMA) at ≈ 1 Hz in the AH was detected in the perilesional cortex in seven patients at T0. In four of these, ALFMA persisted at T2. In patients with ALFMA, the lesion size was significantly larger than in the rest of the patients, and worse clinical outcome was observed in patients with persisting ALFMA. Our results indicate that temporo-parietal ≈ 10-Hz oscillations are enhanced in the AH during recovery from stroke. Moreover, stroke causes ALFMA, which seems to persist in patients with worse clinical outcome.
format	article
author	Kristina Laaksonen Liisa Helle Lauri Parkkonen Erika Kirveskari Jyrki P Mäkelä Satu Mustanoja Turgut Tatlisumak Markku Kaste Nina Forss
author_facet	Kristina Laaksonen Liisa Helle Lauri Parkkonen Erika Kirveskari Jyrki P Mäkelä Satu Mustanoja Turgut Tatlisumak Markku Kaste Nina Forss
author_sort	Kristina Laaksonen
title	Alterations in spontaneous brain oscillations during stroke recovery.
title_short	Alterations in spontaneous brain oscillations during stroke recovery.
title_full	Alterations in spontaneous brain oscillations during stroke recovery.
title_fullStr	Alterations in spontaneous brain oscillations during stroke recovery.
title_full_unstemmed	Alterations in spontaneous brain oscillations during stroke recovery.
title_sort	alterations in spontaneous brain oscillations during stroke recovery.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/45e432b5ee9e4c48b786de78e6123835
work_keys_str_mv	AT kristinalaaksonen alterationsinspontaneousbrainoscillationsduringstrokerecovery AT liisahelle alterationsinspontaneousbrainoscillationsduringstrokerecovery AT lauriparkkonen alterationsinspontaneousbrainoscillationsduringstrokerecovery AT erikakirveskari alterationsinspontaneousbrainoscillationsduringstrokerecovery AT jyrkipmakela alterationsinspontaneousbrainoscillationsduringstrokerecovery AT satumustanoja alterationsinspontaneousbrainoscillationsduringstrokerecovery AT turguttatlisumak alterationsinspontaneousbrainoscillationsduringstrokerecovery AT markkukaste alterationsinspontaneousbrainoscillationsduringstrokerecovery AT ninaforss alterationsinspontaneousbrainoscillationsduringstrokerecovery
_version_	1718422907184480256

Alterations in spontaneous brain oscillations during stroke recovery.

Ejemplares similares