Epigenome-wide association studies identify DNA methylation associated with kidney function

Epigenome-wide association studies identify DNA methylation associated with kidney function

Genome-wide association studies of kidney function show enrichment of associated genetic variants in regulatory regions. Here, the authors perform epigenome-wide association studies of kidney function and disease, identifying 19 CpG sites significantly associated with these.

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Detalles Bibliográficos
Autores principales: Audrey Y. Chu, Adrienne Tin, Pascal Schlosser, Yi-An Ko, Chengxiang Qiu, Chen Yao, Roby Joehanes, Morgan E. Grams, Liming Liang, Caroline A. Gluck, Chunyu Liu, Josef Coresh, Shih-Jen Hwang, Daniel Levy, Eric Boerwinkle, James S. Pankow, Qiong Yang, Myriam Fornage, Caroline S. Fox, Katalin Susztak, Anna Köttgen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/45e696452b874395a34728e50924938d
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Sumario:Genome-wide association studies of kidney function show enrichment of associated genetic variants in regulatory regions. Here, the authors perform epigenome-wide association studies of kidney function and disease, identifying 19 CpG sites significantly associated with these.

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