Epigenome-wide association studies identify DNA methylation associated with kidney function

Genome-wide association studies of kidney function show enrichment of associated genetic variants in regulatory regions. Here, the authors perform epigenome-wide association studies of kidney function and disease, identifying 19 CpG sites significantly associated with these.

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Autores principales: Audrey Y. Chu, Adrienne Tin, Pascal Schlosser, Yi-An Ko, Chengxiang Qiu, Chen Yao, Roby Joehanes, Morgan E. Grams, Liming Liang, Caroline A. Gluck, Chunyu Liu, Josef Coresh, Shih-Jen Hwang, Daniel Levy, Eric Boerwinkle, James S. Pankow, Qiong Yang, Myriam Fornage, Caroline S. Fox, Katalin Susztak, Anna Köttgen
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/45e696452b874395a34728e50924938d
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spelling oai:doaj.org-article:45e696452b874395a34728e50924938d2021-12-02T17:06:18ZEpigenome-wide association studies identify DNA methylation associated with kidney function10.1038/s41467-017-01297-72041-1723https://doaj.org/article/45e696452b874395a34728e50924938d2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01297-7https://doaj.org/toc/2041-1723Genome-wide association studies of kidney function show enrichment of associated genetic variants in regulatory regions. Here, the authors perform epigenome-wide association studies of kidney function and disease, identifying 19 CpG sites significantly associated with these.Audrey Y. ChuAdrienne TinPascal SchlosserYi-An KoChengxiang QiuChen YaoRoby JoehanesMorgan E. GramsLiming LiangCaroline A. GluckChunyu LiuJosef CoreshShih-Jen HwangDaniel LevyEric BoerwinkleJames S. PankowQiong YangMyriam FornageCaroline S. FoxKatalin SusztakAnna KöttgenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Audrey Y. Chu
Adrienne Tin
Pascal Schlosser
Yi-An Ko
Chengxiang Qiu
Chen Yao
Roby Joehanes
Morgan E. Grams
Liming Liang
Caroline A. Gluck
Chunyu Liu
Josef Coresh
Shih-Jen Hwang
Daniel Levy
Eric Boerwinkle
James S. Pankow
Qiong Yang
Myriam Fornage
Caroline S. Fox
Katalin Susztak
Anna Köttgen
Epigenome-wide association studies identify DNA methylation associated with kidney function
description Genome-wide association studies of kidney function show enrichment of associated genetic variants in regulatory regions. Here, the authors perform epigenome-wide association studies of kidney function and disease, identifying 19 CpG sites significantly associated with these.
format article
author Audrey Y. Chu
Adrienne Tin
Pascal Schlosser
Yi-An Ko
Chengxiang Qiu
Chen Yao
Roby Joehanes
Morgan E. Grams
Liming Liang
Caroline A. Gluck
Chunyu Liu
Josef Coresh
Shih-Jen Hwang
Daniel Levy
Eric Boerwinkle
James S. Pankow
Qiong Yang
Myriam Fornage
Caroline S. Fox
Katalin Susztak
Anna Köttgen
author_facet Audrey Y. Chu
Adrienne Tin
Pascal Schlosser
Yi-An Ko
Chengxiang Qiu
Chen Yao
Roby Joehanes
Morgan E. Grams
Liming Liang
Caroline A. Gluck
Chunyu Liu
Josef Coresh
Shih-Jen Hwang
Daniel Levy
Eric Boerwinkle
James S. Pankow
Qiong Yang
Myriam Fornage
Caroline S. Fox
Katalin Susztak
Anna Köttgen
author_sort Audrey Y. Chu
title Epigenome-wide association studies identify DNA methylation associated with kidney function
title_short Epigenome-wide association studies identify DNA methylation associated with kidney function
title_full Epigenome-wide association studies identify DNA methylation associated with kidney function
title_fullStr Epigenome-wide association studies identify DNA methylation associated with kidney function
title_full_unstemmed Epigenome-wide association studies identify DNA methylation associated with kidney function
title_sort epigenome-wide association studies identify dna methylation associated with kidney function
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/45e696452b874395a34728e50924938d
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