Epigenome-wide association studies identify DNA methylation associated with kidney function
Genome-wide association studies of kidney function show enrichment of associated genetic variants in regulatory regions. Here, the authors perform epigenome-wide association studies of kidney function and disease, identifying 19 CpG sites significantly associated with these.
Guardado en:
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/45e696452b874395a34728e50924938d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:45e696452b874395a34728e50924938d |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:45e696452b874395a34728e50924938d2021-12-02T17:06:18ZEpigenome-wide association studies identify DNA methylation associated with kidney function10.1038/s41467-017-01297-72041-1723https://doaj.org/article/45e696452b874395a34728e50924938d2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01297-7https://doaj.org/toc/2041-1723Genome-wide association studies of kidney function show enrichment of associated genetic variants in regulatory regions. Here, the authors perform epigenome-wide association studies of kidney function and disease, identifying 19 CpG sites significantly associated with these.Audrey Y. ChuAdrienne TinPascal SchlosserYi-An KoChengxiang QiuChen YaoRoby JoehanesMorgan E. GramsLiming LiangCaroline A. GluckChunyu LiuJosef CoreshShih-Jen HwangDaniel LevyEric BoerwinkleJames S. PankowQiong YangMyriam FornageCaroline S. FoxKatalin SusztakAnna KöttgenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Audrey Y. Chu Adrienne Tin Pascal Schlosser Yi-An Ko Chengxiang Qiu Chen Yao Roby Joehanes Morgan E. Grams Liming Liang Caroline A. Gluck Chunyu Liu Josef Coresh Shih-Jen Hwang Daniel Levy Eric Boerwinkle James S. Pankow Qiong Yang Myriam Fornage Caroline S. Fox Katalin Susztak Anna Köttgen Epigenome-wide association studies identify DNA methylation associated with kidney function |
description |
Genome-wide association studies of kidney function show enrichment of associated genetic variants in regulatory regions. Here, the authors perform epigenome-wide association studies of kidney function and disease, identifying 19 CpG sites significantly associated with these. |
format |
article |
author |
Audrey Y. Chu Adrienne Tin Pascal Schlosser Yi-An Ko Chengxiang Qiu Chen Yao Roby Joehanes Morgan E. Grams Liming Liang Caroline A. Gluck Chunyu Liu Josef Coresh Shih-Jen Hwang Daniel Levy Eric Boerwinkle James S. Pankow Qiong Yang Myriam Fornage Caroline S. Fox Katalin Susztak Anna Köttgen |
author_facet |
Audrey Y. Chu Adrienne Tin Pascal Schlosser Yi-An Ko Chengxiang Qiu Chen Yao Roby Joehanes Morgan E. Grams Liming Liang Caroline A. Gluck Chunyu Liu Josef Coresh Shih-Jen Hwang Daniel Levy Eric Boerwinkle James S. Pankow Qiong Yang Myriam Fornage Caroline S. Fox Katalin Susztak Anna Köttgen |
author_sort |
Audrey Y. Chu |
title |
Epigenome-wide association studies identify DNA methylation associated with kidney function |
title_short |
Epigenome-wide association studies identify DNA methylation associated with kidney function |
title_full |
Epigenome-wide association studies identify DNA methylation associated with kidney function |
title_fullStr |
Epigenome-wide association studies identify DNA methylation associated with kidney function |
title_full_unstemmed |
Epigenome-wide association studies identify DNA methylation associated with kidney function |
title_sort |
epigenome-wide association studies identify dna methylation associated with kidney function |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/45e696452b874395a34728e50924938d |
work_keys_str_mv |
AT audreyychu epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT adriennetin epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT pascalschlosser epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT yianko epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT chengxiangqiu epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT chenyao epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT robyjoehanes epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT morganegrams epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT limingliang epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT carolineagluck epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT chunyuliu epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT josefcoresh epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT shihjenhwang epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT daniellevy epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT ericboerwinkle epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT jamesspankow epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT qiongyang epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT myriamfornage epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT carolinesfox epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT katalinsusztak epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction AT annakottgen epigenomewideassociationstudiesidentifydnamethylationassociatedwithkidneyfunction |
_version_ |
1718381669530992640 |