Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis
Abstract Knowledge about the region-specific absorption profiles from the gastrointestinal tract of orally administered drugs is a critical factor guiding dosage form selection in drug development. We have used a novel approach to study three well-characterized permeability and absorption marker dru...
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Autores principales: | Anna Nilsson, Alexandra Peric, Marie Strimfors, Richard J. A. Goodwin, Martin A. Hayes, Per E. Andrén, Constanze Hilgendorf |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/45e76ae7ec17443ea148df3403eb0c61 |
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