Role of cell-type specific nucleosome positioning in inducible activation of mammalian promoters

Nucleosome organisation plays important roles in regulating functional genomic elements. Here, the authors use high-resolution profiling to analyse dynamic nucleosome positioning at inducible and cell-type-specific promoters, providing a global view of chromatin architecture at inducible promoters.

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Autores principales: Agata Oruba, Simona Saccani, Dominic van Essen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/45f1d464110d44cca74836c93ff1fa30
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spelling oai:doaj.org-article:45f1d464110d44cca74836c93ff1fa302021-12-02T14:40:53ZRole of cell-type specific nucleosome positioning in inducible activation of mammalian promoters10.1038/s41467-020-14950-52041-1723https://doaj.org/article/45f1d464110d44cca74836c93ff1fa302020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14950-5https://doaj.org/toc/2041-1723Nucleosome organisation plays important roles in regulating functional genomic elements. Here, the authors use high-resolution profiling to analyse dynamic nucleosome positioning at inducible and cell-type-specific promoters, providing a global view of chromatin architecture at inducible promoters.Agata OrubaSimona SaccaniDominic van EssenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Agata Oruba
Simona Saccani
Dominic van Essen
Role of cell-type specific nucleosome positioning in inducible activation of mammalian promoters
description Nucleosome organisation plays important roles in regulating functional genomic elements. Here, the authors use high-resolution profiling to analyse dynamic nucleosome positioning at inducible and cell-type-specific promoters, providing a global view of chromatin architecture at inducible promoters.
format article
author Agata Oruba
Simona Saccani
Dominic van Essen
author_facet Agata Oruba
Simona Saccani
Dominic van Essen
author_sort Agata Oruba
title Role of cell-type specific nucleosome positioning in inducible activation of mammalian promoters
title_short Role of cell-type specific nucleosome positioning in inducible activation of mammalian promoters
title_full Role of cell-type specific nucleosome positioning in inducible activation of mammalian promoters
title_fullStr Role of cell-type specific nucleosome positioning in inducible activation of mammalian promoters
title_full_unstemmed Role of cell-type specific nucleosome positioning in inducible activation of mammalian promoters
title_sort role of cell-type specific nucleosome positioning in inducible activation of mammalian promoters
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/45f1d464110d44cca74836c93ff1fa30
work_keys_str_mv AT agataoruba roleofcelltypespecificnucleosomepositioningininducibleactivationofmammalianpromoters
AT simonasaccani roleofcelltypespecificnucleosomepositioningininducibleactivationofmammalianpromoters
AT dominicvanessen roleofcelltypespecificnucleosomepositioningininducibleactivationofmammalianpromoters
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