Homeobox B4 gene expression is upregulated by ghrelin through PI3-kinase signaling pathway in rat’s bone marrow stromal cells

Objective. Ghrelin, a 28 amino acid peptide, has diverse physiological roles. Phosphatidylino-sitol-bisphosphate 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) are involved in some of the recognized actions of ghrelin. It has been shown that ghrelin upregulates HOXB4 gene expression but...

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Autores principales: Taherkhani Shokoufeh, Moradi Fatemeh, Hosseini Masoumeh, Alipour Mohsen, Feizi Hadi
Formato: article
Lenguaje:EN
Publicado: Sciendo 2019
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Acceso en línea:https://doaj.org/article/45ffa55d4bd54c9fafe3e433b3c7806e
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spelling oai:doaj.org-article:45ffa55d4bd54c9fafe3e433b3c7806e2021-12-02T16:40:25ZHomeobox B4 gene expression is upregulated by ghrelin through PI3-kinase signaling pathway in rat’s bone marrow stromal cells1336-032910.2478/enr-2019-0008https://doaj.org/article/45ffa55d4bd54c9fafe3e433b3c7806e2019-04-01T00:00:00Zhttps://doi.org/10.2478/enr-2019-0008https://doaj.org/toc/1336-0329Objective. Ghrelin, a 28 amino acid peptide, has diverse physiological roles. Phosphatidylino-sitol-bisphosphate 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) are involved in some of the recognized actions of ghrelin. It has been shown that ghrelin upregulates HOXB4 gene expression but the real mechanism of this effect is not clear.Taherkhani ShokoufehMoradi FatemehHosseini MasoumehAlipour MohsenFeizi HadiSciendoarticleghrelinhoxb4pi3kmapkratbmscsDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 53, Iss 2, Pp 65-70 (2019)
institution DOAJ
collection DOAJ
language EN
topic ghrelin
hoxb4
pi3k
mapk
rat
bmscs
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
spellingShingle ghrelin
hoxb4
pi3k
mapk
rat
bmscs
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Taherkhani Shokoufeh
Moradi Fatemeh
Hosseini Masoumeh
Alipour Mohsen
Feizi Hadi
Homeobox B4 gene expression is upregulated by ghrelin through PI3-kinase signaling pathway in rat’s bone marrow stromal cells
description Objective. Ghrelin, a 28 amino acid peptide, has diverse physiological roles. Phosphatidylino-sitol-bisphosphate 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) are involved in some of the recognized actions of ghrelin. It has been shown that ghrelin upregulates HOXB4 gene expression but the real mechanism of this effect is not clear.
format article
author Taherkhani Shokoufeh
Moradi Fatemeh
Hosseini Masoumeh
Alipour Mohsen
Feizi Hadi
author_facet Taherkhani Shokoufeh
Moradi Fatemeh
Hosseini Masoumeh
Alipour Mohsen
Feizi Hadi
author_sort Taherkhani Shokoufeh
title Homeobox B4 gene expression is upregulated by ghrelin through PI3-kinase signaling pathway in rat’s bone marrow stromal cells
title_short Homeobox B4 gene expression is upregulated by ghrelin through PI3-kinase signaling pathway in rat’s bone marrow stromal cells
title_full Homeobox B4 gene expression is upregulated by ghrelin through PI3-kinase signaling pathway in rat’s bone marrow stromal cells
title_fullStr Homeobox B4 gene expression is upregulated by ghrelin through PI3-kinase signaling pathway in rat’s bone marrow stromal cells
title_full_unstemmed Homeobox B4 gene expression is upregulated by ghrelin through PI3-kinase signaling pathway in rat’s bone marrow stromal cells
title_sort homeobox b4 gene expression is upregulated by ghrelin through pi3-kinase signaling pathway in rat’s bone marrow stromal cells
publisher Sciendo
publishDate 2019
url https://doaj.org/article/45ffa55d4bd54c9fafe3e433b3c7806e
work_keys_str_mv AT taherkhanishokoufeh homeoboxb4geneexpressionisupregulatedbyghrelinthroughpi3kinasesignalingpathwayinratsbonemarrowstromalcells
AT moradifatemeh homeoboxb4geneexpressionisupregulatedbyghrelinthroughpi3kinasesignalingpathwayinratsbonemarrowstromalcells
AT hosseinimasoumeh homeoboxb4geneexpressionisupregulatedbyghrelinthroughpi3kinasesignalingpathwayinratsbonemarrowstromalcells
AT alipourmohsen homeoboxb4geneexpressionisupregulatedbyghrelinthroughpi3kinasesignalingpathwayinratsbonemarrowstromalcells
AT feizihadi homeoboxb4geneexpressionisupregulatedbyghrelinthroughpi3kinasesignalingpathwayinratsbonemarrowstromalcells
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